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Prof Alun Hughes
Cardiometabolic Phenotyping Group, Floor 4
170 Tottenham Court Road
London
W1T 7HA
Tel: +44 20 7679 9432
Appointment
  • Professor of Cardiovascular Physiology and Pharmacology
  • Cardiometabolic Phenotyping Group
  • Institute of Cardiovascular Science
  • Faculty of Pop Health Sciences
Biography

Alun Hughes is currently Professor of Cardiovascular Physiology and Pharmacology, UCL and a visiting professor at Imperial College London. He held a chair in Clinical Pharmacology at Imperial College London from 2001-13. He currently also holds a visiting professorship in the Department of Pharmacology, University of Aarhus, Denmark.

Professor Hughes completed his medical degree (MB, BS) at St Mary's Hospital Medical School in 1983 having obtained a 1st class intercalated BSc degree in Physiology in 1979. He was awarded a PhD from the University of London in 1988 for his work on vascular dopamine receptors. Subsequently  he was a Medical Research Council Training Fellow at  St George's Hospital Medical School, a British Heart Foundation Intermediate Fellow, Senior Lecturer/Reader and subsequently Professor of Clinical Pharmacology at Imperial College London.

His work focuses on the structure and function of the cardiovascular system in health and disease. Previous achievements have included the identification of tyrosine phosphorylation as a regulator of calcium channels in vascular smooth muscle,defining the mechanism of the vasodilator action of thiazide diuretics on the vasculature and the application of wave intensity analysis in man. More recently, he has extended his interests into developing novel imaging and computational methods for the assessment of haemodynamics and cardiovascular function in man in vivo and their application to large scale clinical trials and epidemiological studies, such as Southall and Brent Revisited (SABRE),  the Anglo Scandinavian Cardiac Outcomes Trial (ASCOT), REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL) Trial, the Lifelong Health & Ageing: National Survey of Health and Development and the Avon Longitudinal Study of Parents and Children (ALSPAC).

Professor Hughes was Secretary of the British Hypertension Society from 2004 -2008, President of the European Council for Cardiovascular Research from 2008-2010, and is currently a faculty member and hononary Professor of the Danish Cardiovascular Research Academy (DaCRA).

Research Themes
Teaching Summary


Appointments
01-OCT-2000 – 30-SEP-2013 Professor of Clinical Pharmacology National Heart & Lung Institute Imperial College London, United Kingdom
Academic Background
1988 PhD Doctor of Philosophy – Pharmacology University of London
1983 MBBS Bachelor of Medicine/Bachelor of Surgery – Medicine St Mary's Hospital Medical School
1979 BSc Bachelor of Science – Physiology University of London
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