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Dr Ashwani Jha
4th Floor
Sobell Department of Motor Neuroscience and Movement Disorders
33 Queen Square
London
WC1N 3BG
Appointment
  • Senior Clinical Research Fellow
  • Clinical & Experimental Epilepsy
  • UCL Queen Square Institute of Neurology
  • Faculty of Brain Sciences
Research Themes
Research Summary
I am interested in optimising deep brain stimulation treatment for Parkinson's Disease.  Currently, individualised therapy is difficult because we do not understand the underlying pathophysiology of individual symptoms in PD.  We concentrate on a subgroup of patients with severe disease undergoing surgery for deep brain stimulation (DBS) of the subthalamic nucleus (STN). These patients have the most acute need for individualised therapy and the surgical procedure itself provides aremarkable opportunity to explore the pathophysiological basis of phenotypic variation.
 

We have recently developed a study model which allows us to characterise the underlying dysfunctional brain networks in Parkinson's, based on simultaneous magnetoencephalographic (MEG) and intracranial electrode recordings in Parkinsonian patients. We are now investigating this further, by trying to identify how these brain networks relate to symptoms.

Academic Background
2003 MB.ChB Bachelor of Medicine, Bachelor of Surgery – Medicine University of Edinburgh
2000 BSc Hons Bachelor of Science (Honours) – Physiology University of Edinburgh
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