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Prof Adrian Woolf
Nephro-Urology Unit, UCL Institute of Child Health
30 Guilford Street
London
WC1N 1EH
Appointment
  • Honorary Professor
  • UCL GOS Institute of Child Health
  • Faculty of Pop Health Sciences
Research Themes
Research Summary
I have published 100 original research publications, the great majority of which focus on the field of normal and abnormal kidney development. I have co-edited a book (2003): The Kidney - from Normal Developmental to Congenital Disease. Main recent research projects have included: (with David Long) A study of candidate molecules which modulate dietary programming of early nephrogenesis. (with Steve Wilson) Zebrafish studies of Ofd1, a centrosomal protein mutated in human polycystic kidney disease: an investigation of its role in kidney growth and differentiation (with Larissa Kerecuk and Peter Scambler) Exploring the expression and potential roles of Fras1 and Frem2 in models of kidney diseases affecting the collecting duct lineage. (with Michiel Schreuder) Modelling fetal kidney programming ex vivo. (with David A Long and Luigi Gnudi) Roles of angiopoietins in epithelial-endothelial interactions: using the renal glomerulus as a model system. (with Judith Goodship, Heather Cordell, Tim Goodship, Sally Feather, Rajko Kenda)SNP based sib-pair linkage study to identify loci contributing to vesicoureteric reflux and its associated nephropathy. (with David Long) Exploring how vascular endothelial growth factor enhances the growth and differentiation of the embryonic urinary bladder. (with Laurent Fasano, Helen Skaer, Claire Lye and Dagan Jenkins) Investigating the roles of Teashirt transcription factors in the developing and injured/regenerating mouse renal system. (with Peter Scambler and Jolanta Pitera) Roles for Fras1, a basement membrane-associated protein, in normal differentiation of kidney collecting ducts and glomeruli. (with Peter Scambler and Jolanta Pitera) Gene profiling in renal agenesis.
Teaching Summary
I spend a considerable amount of time nurturing the academic careers of junior clinicians and scientists, having supervised 10 PhD, 3 MD and 2 MSc completed theses, several performed by Paediatric Nephrologists and Urologists as well as by basic scientists. Three of my junior staff became Lecturers at UCL, and one has been promoted to Senior Lecturer at UCL. My trainees have been awarded 11 Studentships/Fellowships from UK funding agencies. I have been a Course Director for the annual Continuing Education Programme in Paediatric Nephrology and Urology held at the UCL Institute of Child Health(1997-present). The course is aimed at physicians and surgeons working in the fields of Paediatric Nephrology and/or Paediatric Urology; parts of the course will also be of interest to other clinicians, including primary care paediatricians who look after children with renal tract disease, and adult nephrologists who are interested in the origins of adult renal disease and who are involved in the continuing care of children and teenagers with renal tract disease. For details of the 2009 course, please visit http://www.ich.ucl.ac.uk/education/short_courses/courses/2S_57 Overview Monday 16th March 2009 (All day): Urology Tuesday 17th March 2009 (All day): Renal physiology and its genetics Wednesday 18th March 2009 (Morning): Renal transplantation Wednesday 18th March 2009 (Afternoon): Workshops Thursday 19th March 2009 (Morning): Stones and Nephrocalcinosis Thursday 19th March 2009 (Afternoon): Nephrotic syndrome Friday 20th March 2009 (All day): Cardiovascular and chronic kidney disease
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