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Prof Donald Peebles
240
Medical School Building
74 Huntley Street
London
WC1E 6AU
Appointment
  • Chair of Obstetrics
  • Maternal & Fetal Medicine
  • Inst for Women's Health
  • Faculty of Pop Health Sciences
Biography

Professor Donald Peebles was appointed Chair and Head of the Research Department of Maternal Fetal Medicine at UCL in 2008. He has a number of research interests that focus on improving the outcomes for women and their babies following complicated pregnancies. Particular research areas include: 1) maternal innate immunity, infection, inflammation and preterm labour 2) the role of hypoxia and inflammation in causation of perinatal brain injury 3) fetal physiology (especially fetal responses to acute and chronic substrate deprivation) and 4) the development of novel molecular and cellular methods for treatment of fetal disease. He has been extensively involved in developing translational research within Women’s Health through leadership roles in UCL/UCLH Institute for Women’s Health, the UCLH Comprehensive Biomedical Research Centre and as Maternity Lead within UCLPartners, UCL’s Academic Health Science Centre. He was appointed as the Obstetric Lead for the London Strategic Clinical Maternity Network in July 2013; key priorities include reducing the stillbirth rate, reducing maternal mortality and morbidity as well as improving women’s experience of maternity services in London. He is a member of the Specialist Maternity CRG and the Preterm Labour Clinical Study Group. He is the President of the Blair Bell Research Society and sits as a member of the RCOG Academic Committee. He has been a Scientific Editor of BJOG, on the RCOG Scientific Committee and sat on several Medical Advisory Panels. In parallel with his research activities he is also a sub-specialty accredited Consultant in Maternal Fetal medicine at UCLH with a particular interest in the management of pregnancy complicated by maternal disease or poor obstetric history and fetal medicine, including fetal therapy, prenatal diagnosis and management of fetal growth restriction.

Research Summary

For the past 5 years I have been the UCL Chair of Maternal Fetal Medicine leading a Department of 20 clinicians and scientists. Current research includes studies of 1) maternal innate immunity, infection, inflammation and preterm labour 2) the role of hypoxia and inflammation in causation of perinatal brain injury 3) fetal physiology (especially fetal responses to acute and chronic substrate deprivation) and 4) the development of novel molecular and cellular methods for treatment of fetal disease. Current projects include a first in human study of maternal gene therapy to treat severe intrauterine fetal growth restriction; a case control study to define the interaction between the maternal vaginal/cervical microbiome and cervical innate immunity in the aetiology of preterm labour and preclinical studies to define novel therapies for fetal brain injury.

Teaching Summary

My current teaching related activities include:

Lead for Clinical Academic Training Programme in Womens Health, UCL: currently 3 CLs, 3 ACFs.

Academic representative on the UCLP TRainining Programme Management Committee for Obstetrics and Gynaecology (2008 - ) I am an active member of the TPMC and was extensively involved in the preparation of the successful bid by UCLPartners to become the Lead provider of postgraduate training for NCl and NE London in 2011.

Module Lead IfWH MSc Pregnancy and Childbirth

Member Institute of Women’s Health Undergraduate Committee

Member Institute of Women’s Health Postgraduate Committee 

I supervise 2 PhD students

Supervise and teach 3 RCOG recognised subspecialty trainees in Materno-Fetal Medicine

I am an Academic Mentor

Undergraduate teaching/mentorship 2 hours/week

Academic Background
1995 MRCOG Member of the Royal College of Gynaecologists – Obstetrics and Gynaecology Royal College of Obstetricians & Gynaecologists
1994 MD Doctor of Medicine – Medicine University of London
1988 MA Master of Arts – Clinical Medicine University of Cambridge
1986 MBBS Bachelor of Medicine/Bachelor of Surgery – Clinical Medicine University of London
1983 BA Bachelor of Arts – History of Art University of Cambridge
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