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Dr Daniel Stuckey
Centre for Advanced Biomedical Imaging (CABI)
Paul O'Gorman Building
72 Huntley Street,
London
WC1E 6DD
Tel: 0203 108 2041 - Ext: 46921
Appointment
  • Senior Research Associate
  • Metabolism & Experi Therapeutics
  • Div of Medicine
  • Faculty of Medical Sciences
Biography

Prior to joining UCL in 2013, Daniel worked with Prof. Michael Schneider at Imperial College London’s Biological Imaging Centre. He lead preclinical cardiac imaging for the National Heart and Lung Institute and investigated cell therapy, diffuse cardiac fibrosis, stress cardiomyopathy, hypertrophic cardiomyopathy and transgenic models of disease using MRI, ultrasound and optical tomography.

Daniel studied for his DPhil at The University of Oxford in the Laboratory of Prof. Kieran Clarke. During his PhD he used MRI to assess the benefits of stem cell therapy for the infarcted heart, tracked the location of iron mircosphere labelled bone marrow stromal cells and cardiac stem cells in the live heart over 16 weeks in vivo and performed extensive characterization of cardiac function after stem cell therapy and in transgenic models of heart disease, including hypertrophic and dilated cardiomyopathy and muscular dystrophy.

Research Groups
Research Summary

Daniel leads pre-clinical cardiovascular imaging at UCL’s Centre for Advanced Biomedical Imaging (CABI). His research focuses on developing and applying novel multi-modality imaging approached for the investigation of cardiomyopathy and therapy. Using serial cardiac MRI, ultrasound and SPECT/CT, Daniel non-invasively investigates the mechanisms that underlie cardiac disease and result in heart failure. His specific area of interest is cardiac regeneration through stem cell therapy – an emerging research field which can benefit enormously from translatable basic science. His ongoing research into enhancement of stem cell homing, retention, viability and differentiation, assessed in vivo using MRI, radionucloid, fluorescent and biolumenescent labelling of donor cells, can provide data essential to current clinical trials of stem cells.

 

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