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Prof David Wheeler
Centre for Nephrology
University College London
Rowland Hill Street
London
NW3 2PF
Tel: 020 7472 6457
Fax: 020 7317 8591
Appointment
  • Professor of Kidney Medicine
  • Internal Medicine
  • Div of Medicine
  • Faculty of Medical Sciences
Research Themes
Research Summary
Patients with chronic kidney disease (CKD) die prematurely, largely as a result of cardiovascular diseases. Observational studies indicate that traditional cardiovascular risk factors do not predict outcomes in such patients. Our work is focussed on characterisation of the cardiovascular changes associated with CKD, exploration of the pathophysiology and identification of novel targets for future therapies. To date we have developed risk equations that accurately predict kidney and patient outcomes in CKD and through a major collaborative effort, have initiated a randomised controlled trial involving over 9000 patients aimed at assessing the benefits of lipid-lowering therapy. Ongoing laboratory based studies have to date identified inflammation, hyperphosphataemia and elevated levels of asymmetric dimethylarginine as potential therapeutic targets.
Teaching Summary
Royal Free Campus lead for 3rd year module (General Medical Specialties). Lead teacher for Nephrology.
Academic Background
1999 FRCP Fellow of the Royal College of Physicians Royal College of Physicians
1991 MD Doctor of Medicine To be updated
1984 MRCP Member of the Royal College of Physicians Royal College of Physicians
1980 MB.ChB Bachelor of Medicine, Bachelor of Surgery To be updated
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