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Dr Juan Casas Romero
Appointment
  • Professor of Cardiovascular Epidemiology
  • Institute of Cardiovascular Science
  • Faculty of Pop Health Sciences
Biography
I trained in medicine in Colombia (1999) and continue to train in cardiovascular science. In the UK, I worked initially as a Clinical Research Fellow in Centre for Clinical Pharmacology at UCL and joined LSHTM in April 2005. Since April 2009 I split my time between the LSTHM and the University College London. At LSTHM, I work as co-director of the British Women's Heart & Health Study and Deputy Co-ordinator editor of the Cochrane Heart Group. At UCL, I worked as a Senior Genetic Epidemiologist at the Genetic Epidemiology group.
Research Summary
My major interest is in the application of the Mendelian randomisation principles  to identify causal factors  in cardiovascular disease and pre-eclampsia. More recently, I am interested in the use of genetics to select and validate therapeutic targets.  For this, I make use of large-scale observational studies that I have established or being involved in the last years, those include:

The UCLEB consortium: A group of cohorts from UCL, LSHTM, Edinburgh and Bristol in which we are currently conducting large-scale genotyping using the Metabochip. Work funded by the British Heart Foundation.  

The GenPE study: a large case-control study in pre-eclampsia. This study has recruited over 3700 cases and 4777 controls and 2800 umbilical cord samples, this  study is still ongoing, for details please see  www.genpe.org. I have recently completed a genome-wide association study in Pre-eclampsia, under the umbrella of the WTCCC2. 

British Women Heart & Health Study: From April 2009 I am working as co-Director of the British Women's Heart & Health Study a cohort of over 4000 women in 23 British towns, resource use to investigate the causes and a consequence of cardiovascular disease.

Cardiovascular disease Latin-America: In collaboration with Dr. Bautista at Wisconsin university, we have established a large consortium of population-based studies from Latin America to evaluate the impact of obesity and cardiovascular disease in the region (http://www.pophealth.wisc.edu/laso/).
Teaching Summary
During my time at LSHTM, I have participated in teaching activities that teaching has span from extended epidemiology, design and analyses of epidemiological studies, study design to genetic epidemiology. During the last five years, I also co-organize the non-communicable disease epidemioloy unit.
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