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Prof Nicholas Freemantle
Department of Primary Care and Population Health
UCL Medical School (Royal Free Campus)
Rowland Hill Street
Tel: +44 (0)20 7794 0500 ex34756
Fax: +44 (0)20 7794 1224
  • Chair of Clinical Epidemiology and Biostatistics
  • Primary Care & Population Health
  • Institute of Epidemiology & Health
  • Faculty of Pop Health Sciences
Research Themes
Research Summary

I lead a programme of research examining health care delivery and practice.  This involves primary and secondary research into interventions to improve the effectiveness and efficiency of health care as received by patients in the NHS and other health care systems.   The programme includes both the evaluation of the effectiveness and cost effectiveness of health care interventions and of interventions that aim to improve the way interventions are used. 

The main theme in my work is the application of research methods to complex problems, using a range of methods including randomised trial methodology, prognostic modelling, quasi-experimental methods and systematic overview.

My work includes contribution to the PRIMENT clinical trials unit and the Research Design Service.

Research Activities

Design and analysis of experimental studies that appropriately reflect the real world

Design and analysis of studies to evaluate research implementation strategies

Design and analysis of studies to inform the evidence based incorporation of pharmaceuticals and other health technologies in clinical practice

Development and application of prognostic models

Development of mixed linear and non linear models

Development of frailty models

Application and interpretation of quasi-experimental methods 

Methodological approaches for meta analysis and mixed treatment comparisons

Application of research findings in health policy

Teaching Summary

I have had a long standing role teaching on courses supported by WHO on economic valuation, focussing particularly on the design and analysis of  randomised trials and meta analysis.  I supervise PhDs in relevant areas.


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