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Prof Nicoletta Kessaris
WIBR, Cruciform Building
Gower Street
London
WC1E 6BT
Tel: 020 7679 6737
Fax: 0207 209 0470
Appointment
  • Professor of Neuroscience
  • Wolfson Inst for Biomedical Research
  • Div of Medicine
  • Faculty of Medical Sciences
Research Themes
Research Summary
We study neuronal development during embryogenesis and in the adult brain. We focus on three regions in the forebrain: the cortex, the basal forebrain and the olfactory bulb. We examine the genetic basis of neuronal subtype specification, migration, differentiation and circuit integration. Using genetic tools we fate-map precursor cells in the embryonic brain and identify their neuronal progeny. We tag and purify neuronal subtypes in order to identify genes involved in their development. We manipulate gene function using loss- and gain-of-function approaches. We are also developing genetic tools to trace neuronal connections in vivo and manipulate neuronal activity in order to examine participation in neuronal circuits. These tools will also provide us with an unprecedented ability to interfere with neuronal function in free moving animals.
Academic Background
1998 PhD Doctor of Philosophy – Genetics University of Cambridge
1993 MSc Master of Science – Biochemistry King's College London
1992 BSc Bachelor of Science – Microbiology Imperial College of Science, Technology and Medicine
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