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Dr Rachel Knowles
UCL Institute of Child Health
30 Guilford Street
Tel: 020 7905 2278
  • Clinical Research Fellow
  • ICH Pop, Policy & Practice Prog
  • Institute of Child Health
  • Faculty of Pop Health Sciences

Dr Rachel Knowles qualified in Medicine at Edinburgh University in 1991, completed vocational training in General Practice and Community Paediatrics in Edinburgh and London in 1998, and finished specialist training in Public Health in London in 2004. She obtained a Masters in Medical Anthropology (Brunel University) in 1998 and Public Health (LSHTM) in 2004. She holds an Honorary Consultant appointment at Great Ormond St Hospital. Her PhD thesis, completed at UCL, modelled survival for a UK-wide cohort of children born with congenital heart defects.

Rachel started working at UCL Institute of Child Health in 2001 and was awarded an MRC Clinical Research Training Fellowship in Health of the Public (2003-2007).  She has been Senior Medical Adviser to the British Paediatric Surveillance Unit since 2003 and an expert member of the London Bloomsbury Research Ethics Committee since 2007. Rachel currently sits on the Joint Standing Committee on Congenital Hypothyroidism for the NHS Newborn Blood Spot Screening programme (Public Health England). She was a member of the NICE Guideline Development Group for Antenatal Care in 2006-2008 and contributed to the Evidence Update in 2013.

Research Groups
Research Themes
Research Summary

Rachel's research is concerned with the epidemiology and childhood outcomes of disorders which have their origins in early childhood. It includes a focus on population surveillance and screening, as well as investigating the impact on children's survival and quality of life of living with chronic conditions such as congenital heart defects, congenital adrenal hyperplasia and primary congenital hypothyroidism.

Rachel has been involved in cross-disciplinary collaborations with paediatric clinical specialists, health economists and statisticians. Her work involves applying a range of epidemiological and qualitative methodologies to explore the role of preventive and clinical management services in achieving health gain for children and their families. 

Rachel leads the UK Collaborative Study on Congenital Hypothyroidism and is a Co-Investigator for the new birth cohort study Life Study (led by Professor C Dezateux, UCL-Institute of Child Health) and the Infant Hearts Study (led by Dr K Brown, Great Ormond Street Hospital).

  Honorary Consultant   Great Ormond St Hospital NHS Trust, United Kingdom
  Senior Medical Adviser   British Paediatric Surveillance Unit (BPSU), United Kingdom
Academic Background
2010 PhD Doctor of Philosophy – Epidemiology University College London
2004 FEL Fellowship – Public Health  
2000 MSc Master of Science – Public Health London School of Hygiene and Tropical Medicine
1998 MSc Master of Science – Medical Anthropology Brunel University
1995 MRCGP Member of the Royal College of General Practioners – General Practice Royal College of General Practioners
1994 DCH Diploma of Child Health – Child Health University of Edinburgh
1991 MB.ChB Bachelor of Medicine, Bachelor of Surgery – Clinical Medicine University of Edinburgh
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