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Dr Sven Bestmann
33 Queen Square
London
WC1N3BG
Tel: 0044 203 108 0047
Fax: 0044 20 7278 9836
Appointment
  • Professor
  • IoN Motor Neurosci & Mov Disorders
  • Institute of Neurology
  • Faculty of Brain Sciences
Research Themes
Research Summary
A fundamental feature of our behaviour is the use of predictions about our environment to prepare and specify actions in advance of an event. The inability to use these predictions may result in impairments of action, such as in Parkinson's Disease or Schizophrenia. Our current research asks how prior information and predictions about events bias activity in the human motor system, to transform decision into actions. We use a combination of transcranial magnetic stimulation (TMS) and functional neuroimaging (fMRI, EEG, MEG) to study cortical connectivity and large-scale activity changes during decision implementation and action preparation / selection. To this end, we have pioneered the use of concurrent TMS-fMRI for studying causal interactions between remote but interconnected regions of the human brain. Our labs are located in Queen Square 33, 3rd floor. Our imaging studies are conducted at the Wellcome Trust Centre for Neuroimaging (FIL, www.fil.ion.ucl.ac.uk), which is just across the Square. We use the following approaches: * - Studies of corticospinal excitability, using TMS * - Studies of inter-regional causal interactions, using concurrent TMS-fMRI * - Model-based analyses of action preparation and selection * - Studies of dynamic activity changes during decision implementation and action preparation, using electroencephalography (EEG) and magentoencephalography (MEG)
Academic Background
2004 PhD Doctor of Philosophy – Neurology University College London
2000 BSc Bachelor of Science – Psychology Die Heinrich-Heine-Universit├Ąt
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