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Dr Spyridon Gerontas
UCL Biochemical Engineering
Bernard Katz Building
Tel: 020767937745
  • Research Associate
  • Dept of Biochemical Engineering
  • Faculty of Engineering Science
Research Summary

I am a biochemical engineer with expertise in the mathematical modelling of bioprocess unit operations currently employed as a Post-Doctoral Research Associate at the Department of Biochemical Engineering, UCL.

After completing my undergraduate studies in Chemical Engineering at the National Technical University of Athens, Greece, I conducted postgraduate studies at the Department of Biochemical Engineering at University College London, UK. My doctorate focused on the field of tissue engineering. I developed mathematical models to predict the mass transfer requirements of a prototype bioreactor for the formation of tissue-engineered arteries. Novel ultra scale-down experiments were conducted to determine the parameters needed for such models using small quantities of cells. Additionally, I enhanced my knowledge in computational fluid dynamics and mathematical programming as well as in laboratory techniques most notably human cell culture, 3D cell culture, flow cytometry and oxygen / pH optical sensing.


The main area of my research as a Post-Doctoral Research Associate in the EPSRC Centre for Innovative Manufacturing in Emergent Macromolecular Therapies hosted at University College London in collaboration with Imperial College London lies in the modelling of bioprocess unit operations. As a member of this team, I am involved in the integration of mathematical models and experimentation that can predict the manufacturing performance (e.g. yield, purity) of a sequence of industrial scale chromatographic steps as a function of critical process parameters (e.g. pH, ionic strength, linear velocity). Furthermore, I assist PhD and MSc students in developing computational bioprocess models essential for their studies.


My goal as biochemical engineer is to apply theoretical, experimental and computational methods for the design, evaluation and optimisation of bioprocess unit operations in collaboration with chemists, life scientists, mechanical engineers and surgeons.


Academic Background
2007 PhD Doctor of Philosophy – Biochemical Engineering University College London
2000 BSc Bachelor of Science – Chemical Engineering National Technical University of Athens
2000 MSc Master of Science – Chemical Engineering National Technical University of Athens
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