Sarah graduated in biochemistry and medicine in Edinburgh, and was awarded the University Prize for Biological Sciences for BSc for highest First class degree, and 9 other prizes at the University of Edinburgh Medical School including the Gold Medal for most distinguished MBChB graduate and the Hewlett-Packard Prize for top Scottish Graduate. Sarah has worked on research into neurodegenerative diseases since her PhD as an MRC clinical training fellow at UCL (1996 – 1999). Her PhD work produced 11 peer-reviewed publications, three of which have over 200 citations. After near-completion of her clinical training in neurology and neurogenetics (1999-2003), she was successful in obtaining a Department of Health National Clinician Scientist Fellowship in the Dept of Neurodegenerative Disease, Institute of Neurology, UCL in 2002. Sarah was made a UCL Clinical Senior Lecturer and Hon. Consultant Neurologist in 2003, and promoted to Reader in 2007 and Professor in 2009.  In 2006, Sarah was awarded one of the first HEFCE/NIHR New Blood Clinical Senior Lecturerships, and in the last 5 years has generated over £7 million grant funding for her research. Since establishing her own independent research group in 2003, she has published over 160 peer-reviewed publications (76 of these in 2008-2012), including senior-author papers in high impact journals such as Molecular Cell, Lancet Neurology, Nature Communications, Journal of Experimental Medicine, and PNAS.  Her research has been the subject of a review article in New England Journal of Medicine, scientific articles in The Economist, Lancet Neurology, Nature Reviews Molecular Cell Biology and Scientific American, and has had widespread lay media coverage. Sarah serves on executive advisory panels including the UK HD association, the European HD Network and to NINDS/NIH.