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Dr Sunniyat Rahman
Lab 305
UCL Cancer Institute
72 Huntley Street
  • Research Associate
  • Research Department of Haematology
  • Cancer Institute
  • Faculty of Medical Sciences

I studied for a PhD at Imperial College London where my thesis described a new epigenetic-based mechanism for arsenic-induced carcinogenesis. This was funded by a scholarship from the MRC-PHE Centre for Environment and Health. As an undergraduate, I read Biochemistry at the University of Oxford (Queen's) and wrote my masters dissertation on the identification of novel targets for the transcription factor FOXP1.  

Research Themes
Research Summary

My research is focused on the discovery of novel epigenetic and genetic aberrations that drive T-cell acute lymphoblastic leukaemia (T-ALL), particularly those that impinge on the transcriptional control of proto-oncogenes and tumour suppressors. T-ALL is a haematopoietic malignancy (blood cancer), that arises from the cellular transformation of T-cell progenitors – the cells that mature into functional T-cells. My experiments utilise patient samples, bespoke next-generation sequencing, classical molecular biology and biochemical assays to interrogate T-ALL, in an effort to identify new mechanisms by which this leukaemia occurs. My overall research aim is to use such discoveries to help personalise and stratify treatment for T-ALL. 

Academic Background
2015 PhD Doctor of Philosophy – Clinical Medicine Imperial College of Science, Technology and Medicine
2009 M. Biochem Master of Biochemistry – Biochemistry University of Oxford
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