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Dr Tom Jacques
Institute of Child Health UCL
30 Guildford Street
  • Reader in Paediatric Neuropathology
  • ICH Development Bio & Cancer Prog
  • UCL GOS Institute of Child Health
  • Faculty of Pop Health Sciences
Research Summary
The aim of our group is to understand the development of paediatric brain diseases and in particular the roles of neural stem cells in these diseases. We have focussed on brain tumours and epilepsy. Recent highlights include demonstrating how initial mutations cause different types of tumour in the brain and the isolation of a pathological stem cell from a human malformation of cortical development.

Keywords: Brain, Brain Tumour, Cancer, Epilepsy,  Focal Cortical Dysplasia, Morphology, Neural stem cells, Neuroanatomy, Neurogenesis,Neuropathology, Progenitors, Stem cells, Temporal lobes

Conditions: Astrocytoma, Brain tumours in children, Focal Cortical Dysplasia, Epilepsy

Methods: Cell culture, Confocal microscopy, Gene expression profiling - tissue level, Histology, Immunohistochemistry, light microscopic techniques, Time-lapse imaging, Stereological analysis
Academic Background
2008 FRCPath Fellow of the Royal College of Pathologists – Neuropathology Royal College of Pathologists, UK
2007 MRCPath Member of the Royal College of Pathologists – Neuropathology Royal College of Pathologists, UK
2000 MRCP Member of the Royal College of Physicians – Medicine Royal College of Physicians
1998 PhD Doctor of Philosophy – Neuroscience University of Cambridge
1997 MB BCh Bachelor of Medicine, Bachelor of Surgery – Medicine/Surgery University of Cambridge
1996 MA Master of Arts – Clinical Medicine University of Cambridge
1992 BA Hons Bachelor of Arts (Honours) – Clinical Medicine University of Cambridge
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