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Dr Tammaryn Lashley
Queen Square Brain Bank
1 Wakefield Street
London
WC1N 1PJ
Tel: 0207 679 4023
Appointment
  • Principal Research Associate
  • Neurodegenerative Diseases
  • UCL Queen Square Institute of Neurology
  • Faculty of Brain Sciences
Biography

Obtaining a BSc (Hons) in Biochemistry from University College Swansea and she subsequently took up a research position at the National Institute of Medical Research (MRC, Mill Hill), focusing on spinal cord regeneration under supervision of Prof Geoff Raisman. She then moved to the Institute of Neurology working under the supervision of Professor Tamas Revesz, initially studying progressive supranuclear palsy and the different tau isoforms. The focus of her work shifted towards two hereditary neurodegenerative diseases familial British dementia (FBD) and familial Danish dementia (FDD). She completed her PhD in 2006 investigating the pathology of FBD and FDD providing detailed information about amyloid formation in the brain in these rare conditions, which have similar neuropathological features to those of Alzheimer’s disease (AD) thus providing a model of AD. She is currently focusing her research on frontotemporal dementias (FTLD) currently funded by the Alzheimer’s Research UK fellowship. FTLD's are a large group of dementia's characterized by the deposition of several different proteins. Initial work was carried out to re-diagnose archival cases with the new classifications set out by the FTLD working group. Comparing the underlying pathology with detailed clinical histories therefore enabling a more accurate diagnosis in life for future patients. Her work has now progressed into investigating how the pathological proteins are involved in FTLD, with particular interest in the proteins TDP-43 and FUS and their role in nuclear transport. 

Research Groups
Research Themes
Teaching Summary

Tammaryn is assisting with the new UCL Dementia MSc (Neuroscience) which is now receiving applications and due to start in September 2016.

Appointments
01-MAY-2016 Alzheimer's Research UK Senior Research Fellow Molecular Neuroscience Institute of Neurology, United Kingdom
Academic Background
2006 PhD Doctor of Philosophy – Neuroscience Institute of Neurology
1995 BSc Hons Bachelor of Science (Honours) – Biochemistry University of Wales, Swansea
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