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Prof Zoe Winters
Charles Bell House
Level 3
43 Foley Street
Fitzrovia
London
W1W7JN
Appointment
  • Div of Surgery & Interventional Sci
  • Faculty of Medical Sciences
Biography

Zoe Winters is the Chief Investigator of the NIHR funded world first randomised trial called MIAMI therapeutic mammoplasty versus mastectomy for multifocal breast cancers. After undergraduate general surgery training in Johannesburg and Cape Town, she won a prestigious national Oxford Nuffield Fellowship to complete her DPhil at the Institute of Molecular Medicine in Oxford. Following this she was the Director of the Patient Reported and Clinical outcomes Research Group in breast surgery at the University of Bristol. She was also the recipient of the first national award for her excellence in surgical research called the King James IV Professorship from the Royal College of Surgeons of Edinburgh. Zoe has worked with the UCL Surgery and Interventional Trials Unit (SITU) since 2014.


Her main focus is developing high quality clinical evidence in breast surgery through novel randomization trial designs using mixed qualitative methods. She developed the world's first feasibility randomised trial in breast reconstruction called QUEST. ZW has also developed the first validated European Quality of Life (QoL) questionnaire for women undergoing breast reconstruction. 


ZW is a board member of the European Organization for Research and Treatment of Cancer (EORTC) QoL group and the International Society of Quality of Life (ISOQOL). She is also a Senior Fellow in Teaching of the Higher Education Academy (SFHEA). 

Research Themes
Research Summary

Zoe Winters has independently established an international research reputation, independently securing grant funding.  As Chief Investigator, she collaborates in the UK, Europe, Australia and USA. Her research investigates clinical evidence in breast cancer surgery and the need for standardized clinical outcomes and validated patient reported outcome measures (PROMS). She also conceives new randomization trial designs. She is regarded as an international expert in clinical trials and Quality of Life (QOL) research.


Main achievements leading to the development of an international research program: Patient-centered outcomes research - evidence for comparative effectiveness in oncoplastic breast cancer surgery (breast reconstruction with or without mastectomy).


  • First European breast reconstruction QoL questionnaire for clinical trials and studies comprising an 8-year collaboration with the European Organization for Research and Treatment of Cancer to produce the EORTC QLQ-BRECON23. Validated using an electronic platform called CHES through the University of Innsbruck.
  • First randomized surgery trial called MIAMI evaluating the oncological safety of using therapeutic mammoplasty compared to standard mastectomy. This is a multi-centre UK feasibility study that also aims to collaborate with USA, Australian and European partners. 
  • First world attempt at evaluating a randomized trial evaluating QoL after types of immediate and delayed breast reconstruction called QUEST. This integrated a QUEST Perspectives Study (qualitative) in collaboration with UCL. 
  • First prospective longitudinal cohort multi-centre UK studies evaluating QoL after immediate back flap implant and autologous breast reconstruction evaluating the effects of adjuvant chest wall radiotherapy.
  • QoL research program development with the University of Sydney attempting to develop a QoL questionnaire validated for all types of breast surgery.
  • Principal Investigator on numerous NCRN portfolio trials 
  • Invited International and National speaker and has over 100 publications comprising research articles, book chapters and reviews.
Teaching Summary

Leadership roles in Teaching 


Senior Fellow of Higher Education Academy (SFHEA), 2017 

Breast Surgery for undergraduate Intercalated BSc in Medicine, 2015-16

Member of the Faculty Quality Evaluation in Teaching (FQET), 2005-2007

Human Disease (Surgery) for undergraduate Dental students, 2000-2004

Breast surgery Student Selected Study Components, 2000-2016 

16 Honorary Clinical Research Fellows, 2007 - 2016

Six Post-graduate degrees


Invited Peer Reviewer 25 journals 

More than 100 published abstracts 


Appointments
01-DEC-2017 – 01-DEC-2020 Professor SIS University College London, United Kingdom
Academic Background
2017 SFHEA ATQ04 - Recognised by the HEA as a Senior Fellow – Surgery University College London
1999 DPhil Doctor of Philosophy – Molecular Biology Worcester College Oxford
1986 FRCS Fellow Of The Royal College Of Surgeons – Surgery Royal College of Surgeons of Edinburgh
1983 BM BCh Bachelor of Medicine & Bachelor of Surgery – Medicine University of Johannesburg
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