UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at http://www.ucl.ac.uk/finance/research/post_award/post_award_contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Neuropsychiatry Group: Brain abnormalities in psychosis
The Group’s focus is on the study of patients with first episode psychosis. This programme of research, in collaboration with Professor Eileen Joyce, aims to describe cognitive and brain structural phenotypes at illness onset in order to exclude the effects of aging, medication and other environmental factors. The study funded by a programme grant from the Wellcome Trust, takes advantage of new imaging methodologies (MTR and diffusion tensor imaging [DTI]) able to detect subtle changes before volumetric changes become apparent. We have completed a 3 year follow-up study of first episode schizophrenia and a study of the corpus callosum using DTI. The follow-up study suggest that, although volumetric brain abnormalities are present at the onset of the disease, there is no conclusive evidence to suggest that they progress in these initial years. The lack of DTI abnormalities in the corpus callosum at this initial stage contrast with the myelin changes detected in chronic patients, suggesting that some neuropathological abnormalities may be progressive, or that they occur only in a subgroup of patients that go on to follow a chronic course.
3 Researchers
 More search options
Head of Group
Themes
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by