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Dr Laurent Bozec
(308) Sussex Wing
Biomaterials and Tissue Engineering, UCL Eastman Dental Inst
University College London, 256 Gr
Tel: 020 3456 1188
  • Senior Lecturer
  • Biomaterials & Tissue Eng
  • Eastman Dental Institute
  • Faculty of Medical Sciences

Laurent Bozec is the Head of Research and Director of the Eastman Centre for Postgraduate Research  at the Eastman Dental Institute,University College London. He is also a  Senior Lecturer in Biophysics and Nanometrology . The first part of his research portfolio involves the characterisation at the nanoscale of connective and mineralised tissues in view to improve both fundamental knowledge and diagnostic markers of diseases such as Scleroderma, Ehlers Danlos and Osteogenesis Imperfecta as well as ageing in collagen. Over the last 10 years, Dr Bozec has also been involved in the translation of SPM measurements to the field of conservation science. Since 2012, the technical portfolio of Dr Bozec has expanded as he has now taken the challenge to expand and democratise the use of Optical Coherence Tomography in the field of dentistry. Working with clinical colleagues at the UCL Eastman Dental Institute, he is interested in using this non-ionising technique for the diagnostics of rare dental conditions (Amelogenesis Imperfecta for example) as well as those hard to diagnose (enamel cracks and early carious demineralisation). Finally, being true to his physics background, Dr Bozec has been using large scale facilities such as Diamond UK and European Synchrotron Facility in Grenoble (France) to calibrate and provide further understanding in the nature of the scattering images provided by OCT. 

Research Summary

Current Research topics in Bozec's group:


  • Nano-Histology of collagen tissues affected by rare syndromes using atomic force microscopy : Ehlers Danlos, Osteogenesis Imperfecta, Scleroderma and ARC Syndrome (with Professor Gissen, Dr Parekh and Dr Stratton - UCL, Professor Grahame and Dr Kazkaz - UCLH)

  • Impact of Advanced Glycation End products on the phyiscal and mechanical properties of collagen tissues (human and model) at the nanoscale. 

  • Development of an AFM-based assay to investigate cellular adhesion (single bacterium and STEM cells) on clinical and non-clinical surfaces. 

  • Damage assessment of historical and modern parchment and cellulose based artefacts - Development of novel conservations strategies. (with Dr Odlyha - Birkbeck College)

  • Evaluation of Optical Coherence Tomography as a diagnostics tool for dentistry and its applications to dental anomalies. Use of Synchrotron Facilities (SAXS & XRD) (With Dr Parekh - UCL, Dr Al-Jawad - QMUL and Drs Cook and Festy - KCL)

  • Failures  and bleaching of dental enamel:  diagnostics and modelling.


As a keen Researcher and Mentor, i am always interested in new applications of nanometrology in the field of Materials Science and Regenerative Medicine and encourage potential PhD applicants to contact me directly.


Finally, i have a strong interest in transmitting our basic research to  future generations and , as such, am keen to support any public engagement activities with school, or patients groups for example.


Additional links:


LCN: https://www.london-nano.com/our-people

SEAHA: http://www.seaha-cdt.ac.uk/supervisors/ 

Reseach Gate : https://www.researchgate.net/profile/Laurent_Bozec?ev=hdr_xprf

LinkedIn: https://www.linkedin.com/profile/public-profile-settings?trk=prof-edit-edit-public_profile

Teaching Summary

29-JUL-2015 Head of Research Eastman Dental Institute University College London, United Kingdom
01-OCT-2013 Senior Lecturer in Biophysics and Nanometrology Biomaterials & Tissue Engineering - Eastman Dental Institute University College London, United Kingdom
01-SEP-2007 Lecturer Biomaterials and Tissue Engineering Eastman Dental Institute - University College London, United Kingdom
01-SEP-2005 – 31-AUG-2007 Senior Research Fellow Medicine / London Centre for Nanotechnology University College London, United Kingdom
11-OCT-2002 – 31-AUG-2007 Research Fellow Medicine / London Centre for Nanotechnology University College London, United Kingdom
Academic Background
2003 PhD Doctor of Philosophy – Applied Physics University of Lancaster
1999 BSc Hons Bachelor of Science (Honours) – Applied Physics Nottingham Trent University
1997 HDIP Higher Diploma – Instrumental Techniques Universite de Rennes I
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