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Dr Laurent Bozec
(308) Sussex Wing
Biomaterials and Tissue Engineering, UCL Eastman Dental Inst
University College London, 256 Gr
London
WC1X 8LD
Tel: 020 3456 1188
Appointment
  • Senior Lecturer
  • Biomaterials & Tissue Eng
  • Eastman Dental Institute
  • Faculty of Medical Sciences
Biography

Laurent is a Senior Lecturer in Biophysics and Nanometrology at the Eastman Dental Institute – University College London. During his PhD at Lancaster University under the guidance of Dr Pollock, he was introduced to Atomic Force Microscopy as a novel surface characterisation technique and went onto developping a novel infrared-based spectroscopic AFM technique in collaboration with the late Dr Hammiche. During his time at Lancaster, he also develpped expertise in Scanning Thermal Microscopy (SThM) and more specially in AFM based Locaslised Thermal Analysis (LTA). He joined UCL in 2002 as a PDRA under the guidance of Professor Mike Horton, where he developped a portfolio of research related to the SPM and collagen based materials. During his early years in UCL and subsequently at the London Centre for Nanotechnology, he managed the suite of AFMs and developped a training program that has now been proposed to a wide number aspiring AFM users. His current research is centered on the nano-metrology of collagen in health and disease including ageing and syndromes with the aim of developping SPM as part of a clinical diagnostics suite. Other research interests include nanoscale characterisation of (bio)materials, interactions between cells/bacteria with implants' surfaces with a particular strong focus on antimicrobial resistance (AMRs). Finally, he has also been involved in developping an AFM based damage assessment of collagen-based artefacts for application in Cultural Heritage

Research Summary

Current Research topics in Bozec's group:

 

  • Nano-Histology of collagen tissues affected by rare syndromes using atomic force microscopy : Ehlers Danlos, Osteogenesis Imperfecta, Scleroderma and ARC Syndrome (with Professor Gissen, Dr Parekh and Dr Stratton - UCL, Professor Grahame and Dr Kazkaz - UCLH)

  • Impact of Advanced Glycation End products on the phyiscal and mechanical properties of collagen tissues (human and model) at the nanoscale. (with Professor Birch - UCL)

  • Development of an AFM-based assay to investigate cellular adhesion (single bacterium and STEM cells) on clinical and non-clinical surfaces. (with Professor Donos, Dr Brett and Dr Spratt - UCL)

  • Damage assessment of historical and modern parchment samples - Development of novel conservations strategies. (with Dr Odlyha - Birkbeck College)

  • Evaluation of Optical Coherence Tomography as a diagnostics tool for dentistry and its applications to dental anomalies. Use of Synchrotron Facilities (With Dr Parekh - UCL, Dr Al-Jawad - QMUL and Drs Cook and Festy - KCL)

  • Failures  and bleaching of dental enamel:  diagnostics and modelling. (with Professor Van der Heijden and Dr McDonalds - UCL)

 

As a keen Researcher and Mentor, i am always interested in new applications of nanometrology in the field of Materials Science and Regenerative Medicine and encourage potential PhD applicants to contact me directly.

 

Finally, i have a strong interest in transmitting our basic research to  future generations and , as such, am keen to support any public engagement activities with school, or patients groups for example.

 

Additional links:

 

LCN: https://www.london-nano.com/our-people

SEAHA: http://www.seaha-cdt.ac.uk/supervisors/ 

Reseach Gate : https://www.researchgate.net/profile/Laurent_Bozec?ev=hdr_xprf

LinkedIn: https://www.linkedin.com/profile/public-profile-settings?trk=prof-edit-edit-public_profile

Teaching Summary


Appointments
29-JUL-2015 Head of Research Eastman Dental Institute University College London, United Kingdom
01-OCT-2013 Senior Lecturer in Biophysics and Nanometrology Biomaterials & Tissue Engineering - Eastman Dental Institute University College London, United Kingdom
01-SEP-2007 Lecturer Biomaterials and Tissue Engineering Eastman Dental Institute - University College London, United Kingdom
01-SEP-2005 – 31-AUG-2007 Senior Research Fellow Medicine / London Centre for Nanotechnology University College London, United Kingdom
11-OCT-2002 – 31-AUG-2007 Research Fellow Medicine / London Centre for Nanotechnology University College London, United Kingdom
Academic Background
2003 PhD Doctor of Philosophy – Applied Physics University of Lancaster
1999 BSc Hons Bachelor of Science (Honours) – Applied Physics Nottingham Trent University
1997 HDIP Higher Diploma – Instrumental Techniques Universite de Rennes I
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