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Dr Ariane Chapgier
The Cancer Institute, UCL
72 Huntley Street
  • Senior Teaching Fellow
  • Div of Medicine
  • Faculty of Medical Sciences

Dr Ariane L.A. Chapgier holds a PhD both in Immunology and Human Genetics. Her career is all about dissecting molecular mechanisms required for the immune response, embryonic stem cell differentiation and epigenetics. 

She published many papers with Jean-Laurent Casanova on the genetic predispositions to infectious diseases in human. She then got interested in stem cell research and cardiovascular development and joined the team of Peter Scambler to study the role of the histone chaperone HIRA during cardiac development. During her postdoctoral studies, Ariane developed collaborations within the epigenetic field, and she obtained an EMBO fellowship to join the laboratory of David C. Allis for six months. She was then awarded a BHF Intermediate Basic Science Research Fellowship at the UCL Institute of Child Health along with an honorary lectureship. Ariane was then recruited as a principal research associate at the UCL Cancer Institute where she leads a research on the effects of Inflammation on human induced pluripotent stem cell differentiation towards primitive and definitive hematopoiesis.

Research Summary

Dr Ariane L.A. Chapgier is now focused on the Genetics and the Epigenetics of the innate immune response in the context of inflammation and infectious diseases. She is interested in the role that inflammation has on stemness and differentiation in human. As well, Ariane is back working on the human genetics predisposition to infectious diseases.

Teaching Summary

Ariane is the interim director for the master of Clinical Drug Development (CDD) at UCL. She leads two modules in drug discovery and the module in the Genetics and Epigenetics of human diseases. These modules are shared across different master programmes at UCL.

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