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Dr Ariane Chapgier
The Cancer Institute, UCL
72 Huntley Street
Dr Ariane Chapgier profile picture
  • Honorary Associate Professor
  • Div of Medicine
  • Faculty of Medical Sciences

Dr Ariane L.A. Chapgier holds a PhD both in Immunology and Human Genetics. Her career is all about dissecting genetic and epigenetic mechanisms required for the immune response and embryonic stem cell differentiation. 

She published many papers with Jean-Laurent Casanova on the genetic predispositions to infectious diseases in human. She then got interested in stem cell research and cardiovascular development and joined the team of Peter Scambler to study the role of the histone chaperone HIRA during cardiac development. During her postdoctoral studies, Ariane developed collaborations within the epigenetic field, and she obtained an EMBO fellowship to join the laboratory of David C. Allis for six months. She was then awarded a BHF Intermediate Basic Science Research Fellowship at the UCL Institute of Child Health along with an honorary lectureship. Ariane was then recruited as a principal research associate at the UCL Cancer Institute where she leads her research on the effects of Inflammation on human induced pluripotent stem cell differentiation towards primitive and definitive hematopoiesis. She is now an honorary associate professor in the division of Medicine.

Research Summary

Dr Ariane L.A. Chapgier is now focused on the genetics and the epigenetics of the innate immune response in the context of inflammation and infectious diseases. She is interested in the role that inflammation has on stemness and differentiation in human. As well, Ariane is back working on the human genetic predispositions to infectious diseases.

Teaching Summary

For two years, Ariane has been the director of the post-graduate Clinical Drug Development (CDD) programme at UCL. It includes MSc, MRes and PG diploma and certificate. She led two modules in drug discovery (MEDC0047 and MEDC0048) for this programme and was responsible for the research project modules MEDC0072 and MEDC0073.

She designed and still leads the module the Genetics and Epigenetics of human diseases (MEDC0085) for MSc students. 

Finally, she is a tutor for the undergraduate bioinformatics module MEDC0106 in which she still teaches Genetics and Epigenetics.

Different programmes share MEDC0085 and MEDC0106 at UCL.

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