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Prof Alun Hughes
Floor 5, MRC LHA at UCL
1 – 19 Torrington Place
Prof Alun Hughes profile picture
  • Professor of Cardiovascular Physiology and Pharmacology
  • Population Science & Experimental Medicine
  • Institute of Cardiovascular Science
  • Faculty of Pop Health Sciences

Alun Hughes is Professor of Cardiovascular Physiology and Pharmacology at UCL Institute of Cardiovascular Science. He is also Head of the Department of Population Science & Experimental Medicine in the UCL Institute of Cardiovascular Science, Director of the British Heart Foundation 4-year PhD programme, and Associate Director of the MRC Unit for Lifelong Health and Ageing at UCL. He is also a visiting professor at the National Heart & Lung Institute, Imperial College London, the Menzies Institute for Medical Research, University of Tasmania & the Department of Pharmacology, University of Aarhus, Denmark.

Professor Hughes completed his medical degree (MB, BS) at St Mary's Hospital Medical School in 1983 having obtained a 1st class intercalated BSc degree in Physiology in 1979. He was awarded a PhD from the University of London in 1988 for his work on vascular dopamine receptors. Subsequently  he was a Medical Research Council Training Fellow at  St George's Hospital Medical School, a British Heart Foundation Intermediate Fellow, Senior Lecturer/Reader and subsequently Professor of Clinical Pharmacology at Imperial College London before moving to UCL.

Professor Hughes was Secretary of the British Hypertension Society from 2004 - 2008, President of the European Council for Cardiovascular Research from 2008-2010, and Treasurer of the Artery Society 2019 - 2021. He is currently chair of the Artery Council, and a faculty member and hononary Professor of the Danish Cardiovascular Research Academy (DaCRA).

Research Summary

Professor Hughes' work focuses on the structure and function of the cardiovascular system in health and disease. Previous achievements have included the identification of tyrosine phosphorylation as a regulator of calcium channels in vascular smooth muscle,defining the mechanism of the vasodilator action of thiazide diuretics on the vasculature and the application of wave intensity analysis in man. More recently, he has extended his interests into developing novel imaging and computational methods for the assessment of haemodynamics and cardiovascular function in man in vivo and their application to large scale clinical trials and epidemiological studies, such as Southall and Brent Revisited (SABRE),  the Anglo Scandinavian Cardiac Outcomes Trial (ASCOT), REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL) Trial, the Lifelong Health & Ageing: National Survey of Health and Development, the National Child Development Study and the Avon Longitudinal Study of Parents and Children (ALSPAC).

Teaching Summary

Course director for the MRC LHA PhD programme (2018 - )

Course director of UCL 4 year British Heart Foundation PhD programme (2017 - )

Module Organizer for Clinical Case Studies in Cardiovascular Medicine in iBSc in Cardiovascular Science (CARD 3001) (2017 - 2018)

Co-lead for Clinical Case Studies in Cardiovascular Medicine in iBSc in Cardivascular Science (CARD 3001) (2016 - 2017)

Deputy director of iBSc in Cardivascular Science (2013 - )

Module tutor for Heart & Circulation (PHOL 3002) (2013 - )

Personal tutor for MBBS students (2013 - )

Supervisor for EPSRC Doctoral training programme in Medical Imaging

Supervisor for MRC Doctoral training programme in Experimental and Personalized Medicine

Supervisor for Wellcome Trust PhD Programme for Clinicians

01-OCT-2000 – 30-SEP-2013 Professor of Clinical Pharmacology National Heart & Lung Institute Imperial College London, United Kingdom
Academic Background
1988   Doctor of Philosophy University of London
1983   Bachelor of Medicine/Bachelor of Surgery St Mary's Hospital Medical School
1979   Bachelor of Science University of London
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