Argyro’s current research focuses on the Mathematical Modelling of Polymer degradation applied to Plastic Museum Artefacts in the framework of the European research project called COMPLEX. She investigates the inter-relationships between different physical and chemical mechanisms which contribute to the degradation of objects in museums and collections over time. Her research relies on the Mathematical modelling of the mechanisms and transport phenomena which take place during degradation such as migration of plasticiser, physical damage degradation and photodegradation. 

Argyro worked initially in the field of Biophysics at the National Hellenic Research Foundation, where her role focused on the study of the interaction of the antihypertensive drug of Candesartan with lipid bilayers by using solid state 31P NMR spectroscopy and simulations. During her MSc, she investigated experimentally the effect of pre-treatment of Barley straw with sulphuric acid for Hydrogen production. Her PhD focused on modelling the operation of III–V Quantum Well Field Effect Transistor devices both in the ballistic and drift regimes. She performed both first-principles and compact modelling calculations of nanoscaled FETs and analysed the relative merits of each.