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Dr Adam Pennycuick
Appointment
  • Wellcome Trust Clinical Training Fellow
  • Respiratory Medicine
  • Div of Medicine
  • Faculty of Medical Sciences
Biography

Adam is a respiratory physician with a research interest in early lung cancer development. He is a Wellcome funded clinical PhD fellow supervised by Professor Sam Janes and Dr Nicky McGranahan at UCL. Adam leads on bioinformatic analyses within the Janes lab. 


Before studying medicine, Adam completed a Mathematics and Physics degree at the University of Warwick, graduating with first class honours in 2005. He spent 2 years working in aerospace engineering in Bristol. In 2009 he took up a place on King’s College London’s accelerated postgraduate medical course, graduating with distinction in 2013. 


Adam has sought to utilise his technical background for research throughout his medical career. He completed an Academic Foundation Programme in hepatology with Prof. Alberto Sanchez-Fueyo at King’s College London, during which he learned the fundamentals of bioinformatic analysis and published work on transcriptional markers of liver transplant rejection. In 2015 Adam joined UCLH as an Academic Clinical Fellow in Respiratory medicine. In Professor Janes’ lab he developed his bioinformatic skills further, working with a unique cohort of pre-invasive lung cancer patients to understand the molecular changes driving progression to invasive cancer. 


This cohort forms the basis of his current work. Why do some pre-cancerous lesions become cancer whilst others do not? Can we predict which patients will get cancer? What is the role of the immune system in eliminating pre-cancerous lesions, and how can we support it? Answering these questions has enormous potential in developing new strategies for cancer detection, interception and treatment. 


Alongside his clinical and research work, Adam is involved in clinical teaching. He leads Oslr Ltd., a startup aiming to improve coordination and delivery of medical education at the bedside through use of technology. Oslr is supported by UCL Innovation and Enterprise, with offices at King’s Cross. Funding of over £230,000 has been secured to date, with support from InnovateUK, Health Education England, the British Medical Journal, King’s College London, and Jisc. Adam leads a team of developers and business experts to deliver this vision. 

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