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Dr Anai Gonzalez Cordero
  • UCL Sensory Systems and Therapies Fellowship in Stem Cell Biology of the Ear and the Eye
  • Institute of Ophthalmology
  • Faculty of Brain Sciences

I obtained my degree in Developmental Biology in 2008 from University College London and was subsequently awarded a Phd in Stem cell and retinal regeneration from the Wellcome Trust Developmental and Stem Cell Biology programme. Since obtaining my PhD, I continued to develop stem cell therapy for the treatment of blindness and I am now a research fellow developing in vitro models of retinal and auditory organoids derived from human pluripotent stem cells.

Research Summary

My research utilises human pluripotent  stem cell (hPSCs) differentiated into retinal and otic cell types for cell therapy and disease modelling purposes. 

One of my main interest is to understand the behaviour of hPSC-derived photoreceptors following their transplantation into models of retinal degeneration. My research focus is the differentiation of hPSC-derived photoreceptors and RPE cells for transplantation purposes to investigate their integration capacity into the diseased retina. 

Having established retinal organoid cultures that recapitulate normal human eye development in the dish we are now developing similar 3D protocols to differentiate inner ear like structures from hPSCs. hPSC-derived otic and retinal organoids represent the perfect tools to model and understand syndromes affecting both the ear and the eye. In the lab we are particularly interested in investigation the pathophysiology of USH syndrome. 

  Post- Doctoral Research Associate Department of Genetics Institute of Ophthalmology, United Kingdom
Academic Background
2013 PhD Doctor of Philosophy – Developmental Biology University College London
2008 BSc Bachelor of Science – Developmental Biology University College London
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