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Dr Amairelys Barroeta Seijas
UCL Great Ormond Street Institute of Child Health
Tel: +44 (0)207 905 2219
  • Research Associate
  • Infection, Immunity & Inflammation Dept
  • UCL GOS Institute of Child Health
  • Faculty of Pop Health Sciences

In the last two years I have been working as a Research Associate scientist at the UCL Great Ormond Street Institute of Child Health (ICH), the primary research partner of Great Ormond Street Hospital (GOSH) and the largest paediatric centre in Europe dedicated to both clinical and basic scientific research. I have more than 14 years’ laboratory experience in the immunology field with a wide expertise in basic research as well as diagnostics of Primary immune deficiencies.
I began my academic career at the Central University of Venezuela (UCV), where I completed a BSc Hons in Biology in 2007. Thereafter, I got a position also at the Central University of Venezuela as a Research & Teaching assistant in Biochemistry, where I worked for about 6 months before being awarded with a scholarship for my PhD in Italy, where I moved in 2008.
I quickly completed my PhD in Immunology and Applied Biotechnology at the University of Rome Tor Vergata in “Common Variable Immune deficiency in Infancy” (2012). During my PhD I received a Short-term fellowship from the European Society for Immune deficiencies (ESID), so I spent three months at the Royal Free Hospital & University College London where I enriched my PhD data and knowledge on Primary Immune deficiencies (PID).
My first Post-doc fellowship was at the University of Rome La Sapienza, which is one of the top leading research Universities in Italy. There, I investigated the role of dendritic cells in the presentation of tumour-derived antigens and the changes induced by Stem Cell Factor (SCF) in both presentation to T cells and peptide generation. I also studied the role of molecular mediators affecting both angiogenesis and CD8 T cell responses.

Research Summary
Current Gene therapy projects
My current research project is focused on the development of gene therapy protocols for the treatment of primary immune deficiencies, with particular focus on X-linked lymphoproliferative disease (XLP) type 1 and type 2.
What I enjoy the most about my current job at the institute, is that I can be part of a team of people committed to develop ground breaking therapies that change and save lives. This position has allowed me to get the most of my previous experience in immunology, cellular and molecular biology and it is incredibly satisfactory to combine the skills I have acquired during my career to do research that save children’s lives.
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