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Dr Charlie Arber
101 1 Wakefield Street
Department of Neurodegenerative Disease
UCL Institute of Neurology
London
WC1N 1PJ
Appointment
- Alzheimer's Society Research Fellow
- Neurodegenerative Diseases
- UCL Queen Square Institute of Neurology
- Faculty of Brain Sciences
Research Groups
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Research Summary
My work focuses on modelling Alzheimer's disease using human stem cells.
We generate models of dementia using patient derived fibroblasts and cellular reprogramming, together with CRISPR/Cas9 genome editing technologies. We then employ these iPSCs to generate neurons, organoids, astrocytes and microglia.
These models help us to understand the underlying causes of neurodegeneration in dementia. Specifically, my work focuses on neuroinflammation and Amyloid beta biology.
Appointments
| 01-OCT-2019 | Senior Research Fellow | Queen Square Institute of Neurology, United Kingdom | |
| OCT-2008 – NOV-2012 | PhD Stem Cell Neurogenesis | MRC Clinical Sciences Centre | Imperial College London, United Kingdom |
| SEP-2007 – SEP-2008 | MSc Stem Cell Technology | University of Nottingham, United Kingdom |
