Email: portico-services@ucl.ac.uk
Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
- Professor of Molecular Immunology
- Infection, Immunity & Inflammation Dept
- UCL GOS Institute of Child Health
- Faculty of Pop Health Sciences


My research has
involved the elucidation of the molecular
and cellular defects in inherited immunodeficiency disorders which has
resulted in our identification of
several disease causing genes. We are now investigating the functions of
the protein products of these genes, in both health and disease. We are
translating the results of this basic research into new and improved strategies
for treatment, principally by the development
of techniques for the cure of these disorders by somatic gene therapy
techniques.
We have
initiated phase I clinical trials for
the treatment of X-linked severe combined immunodeficiency (SCID), adenosine
deaminase (ADA) deficient SCID, X-linked chronic granulomatous disease (CGD)
and Wiskott-Aldrich syndrome using
gene therapy techniques.
I am currently the UCL Academic Lead for the Zayed Centre for Research into Rare Disease in Children, a joint project between UCL, GOSH and the GOSH Charity.
Student Supervision: I have supervised research students
at BSc, MSc, MPhil and PhD level, seeing more than 20 PhD students to completion.
Lecturing: I have been responsible for teaching on a variety of under-graduate (UG) and post-graduate (PG) courses within and external to UCL throughout the year, including a number of European Summer Schools.
Leadership in Teaching: Between 2011 and 2018 I was Deputy Director (Education) at GOS ICH and Vice-Dean Education in the Faculty of Population Health Sciences at UCL, responsible for the education and training of over 1,000 postgraduate taught and research students across a wide range of health-related disciplines. In 2011, I established, and subsequently directed, the world’s first MSc programme in Cell and Gene Therapy at GOS ICH.
1984 | Doctorat | University College London | |
1978 | Bachelor of Science (Honours) | University of Newcastle upon Tyne |