My research focus in the past decade has been on complex degenerative disorders of the brain, particularly Parkinson’s disease and Frontotemporal dementia. I started my career as a biochemist, investigating the relevance of cell waste disposal in the pathogenesis of Parkinson’s disease. I soon developed a deep interest in bioinformatics and joined the International Frontotemporal Dementia Genetics Consortium (IFGC) analysis team. I realized that biomedical research is currently facing the challenge of translating genetic research into functional knowledge. This translation, which is essential for applying genetics knowledge to the improvement of human health, is somehow hampered by many technical difficulties that make genetic data interpretation and validation neither time nor cost-effective. My research sits at the interface between genetics and functional biology and is aimed at easing the bidirectional flow of information between genetics to functional models through bioinformatics and systems biology pipelines for -omics data processing.