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Appointment
  • Honorary Professor
  • Neuro, Physiology & Pharmacology
  • Div of Biosciences
  • Faculty of Life Sciences
Biography

Prior to moving to London in 2012, I held a University Lectureship at Cambridge (2006-12). Before that, I was a Royal Society Research Fellow (Cambridge and Manchester). 

Research Summary

Brain energy sensing and control, arousal and appetite

Burdakov lab studies brain networks and neural computations that implement efficient and healthy interrelations between behaviour and the environment. We are especially interested in how the brain processes data (e.g. glucose levels, external disturbances) to compute control signals that reconcile vital behaviours (eating, arousal/exploration, sleep) with energy efficiency.

Our experiments focus on widely-projecting neural modules that sense nutrient-related signals and control appetite and arousal (e.g. orexin/hypocretin neurons, and other "brain orchestrators"). Mismatching appetite and arousal to the environment causes some of the most frequent diseases today, such as obesity and sleep disorders that affect around 1:4 people worldwide. 

Our research strategy can be described as "reverse engineering” of neural sensors and controllers at many levels, from components to computations, from molecules to neuronal biophysics to network dynamics to whole-body physiology and behaviour. 

Teaching Summary

I have been teaching undergraduate courses in Medicine and Natural Sciences since 2005

Academic Background
  BA Bachelor of Arts – Physiology University of Oxford
2004 DPhil Doctor of Philosophy – Neurophysiology University of Oxford
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