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- Honorary Senior Lecturer
- Maternal & Fetal Medicine
- Inst for Women's Health
- Faculty of Population Health Sciences
I qualified from the Royal London Medical College and trained in renal and internal medicine before moving to the Department of Anatomy and Developmental Biology, UCL. Here, I obtained my PhD on the control of vascular tone in pregnant women under the supervision of Geoffrey Burnstock. I took up a senior lecturer position in
Obstetric Medicine at Imperial College before returning to UCLH and the Institute for Women's Health as an obstetric physician, specialising in medical disorders in pregnancy.
I am chairman of a NICE Topic Expert Group and of a review group for commissioning and quality outcomes framework for Hypertension in Pregnancy. I am a member of the Independent Advisory Group for maternal, newborn and infant programme, Healthcare Quality Improvement Partnership (HQIP) that reports on maternal deaths in the UK.
My research is aimed at understanding the pathophysiology of the placental disorders pre-eclampsia and fetal growth restriction in order to design an effective prophylaxis and treatment. My group use in vivo methods to study maternal vascular physiology and ex vivo models to study micro-vessel reactivity.
We have contributed to the observations that women who have had pre-eclampsia are at increased risk of future cardiovascular disease and men who father growth restricted offspring are more likely to be insulin resistant. Ongoing work is aimed at understanding the inheritance of an insulin resistant genotype from parent to growth restricted offspring.
I am chief clinical investigator on the MRC funded Stamp trial, investigating the possibility that statins may be beneficial in ameliorating pre-eclampsia.
Other projects are aimed at understanding the pathophysiology of other gestational syndromes and how they predict a woman's future health.
I co-lead an annual MSc on Pregnancy and Childbirth at The Institute for Women's Health and a 3-day course on medical disorders in pregnancy at The Royal College of Physicians. I am senior preceptor for maternal medicine at the Royal College of Obstetricians and Gynaecologists. I supervise PhD students in my group and co-supervise students of collaborators. I lecture on postgraduate courses on maternal medicine around the UK and internationally.
|2006||FRCP||Fellow of the Royal College of Physicians||Royal College of Physicians|
|2003||PhD||Doctor of Philosophy||University College London|
|1987||MRCP||Member of the Royal College of Physicians||Royal College of Physicians|
|1984||MBBS||Bachelor of Medicine/Bachelor of Surgery||London Hospital Medical College|