The maternal medicine research group aims to understand the patho-physiology of gestational syndromes in order to design effective prophylaxis and treatment, to improve pregnancy-outcome and the long term health of mother and baby. In particular, we investigate the metabolic, vascular and immune changes in pregnancy and how they are altered before the onset of pre-eclampsia, gestational diabetes and acute fatty liver of pregnancy.

We use in vivo methods to study maternal vascular reactivity, metabolic response to fasting and exercise and immune profiling.

In collaboration with QMUL we are investigating the influence of paternal phenotype on fetal growth through the inter-generational inheritance of epigenetic marks.

In collaboration with Birmingham and Aston Universities we are investigating whether statins can ameliorate early-onset pre-eclampsia.