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Prof Pier Lambiase
Cardiovascular Genetics Lab
Paul O'Gorman Building
72 Huntley St
Tel: 0203 679 4407
Fax: 0207 573 8847
Prof Pier Lambiase profile picture
  • Professor of Cardiology
  • Clinical Science
  • Institute of Cardiovascular Science
  • Faculty of Pop Health Sciences
Research Summary

My research group is focussed on ventricular arrhythmogenesis in inherited arrhythmia syndromes including Brugada, long QT syndrome and cardiomyopathic disease. This involves in vivo high density mapping studies of the heart using basket catheters, epicardial sock recording and non-invasive ECG Imaging (ECG Vue) in these patients. The basis of Sudden Arrhythmic Death Syndrome is being studied through clinical and genetic screening of affected families and molecular autopsy. Clinical studies also include AF mechanisms,  trials of novel ablation strategies versus conventional techniques & the assessemnt of novel subcutaneous/leadless pacing and defibrillation technologies.

At a more fundamental level, we are investigating the cellular & molecular basis of arrhythmia in ARVC, long QT and Brugada models (in collaboration with Professor Andrew Tinker, UCL & QMUL) & ischaemic heart disease. The in vivo electrodynamics and mechanics of the failing human ventricle are fundamental to the development of ventricular arrhythmia in heart failure patients. This is being investigated using a combination of MR imaging and high density mapping through collaborations with the UCL & KCL imaging sciences groups. Research is supported by project grants and fellowships from MRC, Welcome Trust, BHF, Heart Research UK, Barts Charity and UCL CBRC.

Media Links:http://www.standard.co.uk/news/find-cure-for-heart-fault-which-killed-our-beckie-6924098.html







Teaching Summary

Postgraduate- European Heart Rhythm Association Electrophysiology Course Director, EHRA Training Committee, Boston Scientific HeartStart Course Co-director, London Deanery Cardiology SpR Training Committee for Electrophysiology.

Undergraduate-SSM cardiology and ECG seminars Postgraduate-UCL Course in Emergency Cardiology, London Deanery Electrophysiology and Pacing Training Committee, N.Thames GP training

Academic Background
2003   Doctor of Philosophy University of London
1995   Member of the Royal College of Physicians Royal College of Physicians
1992   Bachelor of Medicine, Bachelor of Surgery University of Oxford
1989   Bachelor of Arts University of Oxford
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