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Dr Daniel Reisel
72 Huntley Street
Tel: 02031082003
Dr Daniel Reisel profile picture
  • Clinical Research Fellow
  • Womens Cancer
  • UCL EGA Institute for Womens Health
  • Faculty of Pop Health Sciences

Specialist Registrar in Gynaecology with broad experience in academic translational research. Focus on the role of hormones across lifespan, systems medicine approach and adaptive and maladaptive epigenetic changes. Multidisciplinary approach to develop digital clinical tools for personalised risk prediction, especially when and how to use 'omics' (genomic, epigenomic, metabonomic approaches) in diagnosis, management and ultimately in the prevention of disease. Other areas of interest include teaching, mentoring, patient-driven digital health, and reproductive ethics. I believe being a doctor is first and foremost about being an attentive listener, understanding what matters for each individual patient at a given moment, and then to enter into dialogue to empower them to make evidence-based choices about their health.

I serve as the Assistant PI and Study Coordinator of the FORECEE (4C) Study, whose purpose is to identify novel ways of predicting and ultimately preventing women's cancer. I contribute to research into the how to best optimise pan-omic testing (genetic, epigenetic, metabonomic etc.) for cancer risk prediction in healthy women and for women with a BRCA alteration. I am also interested in implementation-related themes such as barriers to testing, risk communication and decision-making support, ethical implications, and health behaviour in response to testing. 

Supported by a £20k development grant from UCL, I created a free six-week course called Making Babies in the 21st Century (www.makingbabies.info), which so far has had over 19,000 learners enrolled from over 80 countries. 

In 2016, I set up the Antony Silverstone Fellowship (www.silverstonefellowship.org), to support clinical service improvements at the UCLH Maternity Service that focus on enhancing the patient-provider relationship. 

Research Summary

Epigenetics - often referred to as the science of biological change - offers new ways to understand disease and diagnose it at the earliest possible time. Used in combination with personalised medicine, it has the potential to revolutionise the way we screen and monitor female-specific cancers such as ovarian and endometrial cancers. With the help of new genetic and epigenetic techniques, we are already able to better characterise risk and inform an individual's choice than previously. Much work remains in order to make it clinically meaningful, however, as we are just starting to see the benefit of this approach at the bedside.  

Meanwhile on the laboratory side, we use a number of molecular approaches to attempt to demystify cancer pathology and, in particular, female cancer risk. In January 2015, the Translational Research Group headed by Prof Martin Widschwendter launched an ambitious research programme to identify principal risk factors in hereditary breast and ovarian cancer. The 4C Study has now collected biosamples (buccal, blood and cervical cells) from over 5,000 women, with the aim to improve our ability to predict who is more likely to develop cancer in their lifetime. 

Teaching Summary

I'm passionate about teaching and have a special interest in using blended learning as part of an integrated curriculum. 

I lead the ethics teaching for the two MSc programmes at the Institute for Women's Health and also teach several sessions on the new iBSc in Women's Health. 

I also deliver teaching and training at the UCL Medical School, and since 2014, have been a Reflective Practice Tutor, supporting medical students to develop their reflective reasoning skills.

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