UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at http://www.ucl.ac.uk/finance/research/post_award/post_award_contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
 More search options
Prof David Holder
2.07
Medical Phys and Bioengineering, UCL
Malet Place Engineering Building, Gower St
London
WC1E 6BT
Appointment
  • Professor of Medical Physics and Clinical Neurophysiology
  • Dept of Med Phys & Biomedical Eng
  • Faculty of Engineering Science
Biography


Research Summary

I have had a joint training in Clinical Medicine and Biophysics. I currently hold a joint position as a consultant in Clinical Neurophysiology at UCH and head an interdisciplinary research group in Medical Physics at UCL.

I have been at UCL since 1986 and over this time have pioneered the use of a new medical imaging method, Electrical Impedance Tomography, for imaging brain function and pathology. We have developed instrumentation and image reconstruction software for this purpose. these have been tested and refined in computer simulation, saline filled tanks, humans and anaesthetized animals. We have demonstrated that EIT can image fast electrical activity in the cerebral cortex in the brain, with a resolution of <200 um and 1 msec using non-penetrating electrode mats placed on the brain. Research is actively in progress into using EIT in imaging in normal activity and epilepsy, stroke and peripheral nerves in humans. If successful, this would provide a completely new imaging method which could image fast electrical activity throughout the brain. It could also provide a new portable imaging device which could be used in ambulances or GP surgeries in acute stroke; this could enable the early use of clot-dissolving treatment which would save many lives. The research is currently supported by Glaxo Smith Kline and Blackrock Microsystems, as well as charity and Research Council funds. 

I have been Consultant in Clinical Neurophysiology at UCH since 1997 where I undertake EEG reporting, nerve conduction studies and EMG (electromyography). I have an interest in the development of new methods for diagnosis, such as using machine learning methods for automated analysis of the EEG, or using EIT to assist in a project to treat many conditions by electrical stimulation of autonomic nerves.

Teaching Summary

I teach undergraduate and Master's students in Physics and Medical on courses on Medical Physics and Biophysics. In addition, I train undergraduate, master's and PhD students with backgrounds in Medicine, Engineering, Physics and Maths in research projects in my interdisciplinary bioengineering/neurophysiology research group in the Medical Physics department.

Academic Background
1991 PhD Doctor of Philosophy – Physiology University College London
1984 MA Master of Arts – Biophysics University of California - Berkeley
1978 MBBS Bachelor of Medicine/Bachelor of Surgery – Clinical Medicine To be updated
1975 BA Bachelor of Arts University of Cambridge
Please report any queries concerning the data shown on this page to https://www.ucl.ac.uk/hr/helpdesk/helpdesk_web_form.php
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by