My research interests revolve around the conduct of evidence synthesis, assessment of the certainty of evidence and use of evidence in clinical practice guidelines. I am particularly interested in how we can optimise evidence synthesis using aggregate data, and the application of advanced methods of evidence synthesis such as meta-analysis using individual participant data (IPD). I mostly work with evidence from randomised controlled trials and issues around the synthesis of these; however, I am also interested in secondary use of IPD from RCTs employing methods allowing to draw causal inferences from observational data. Another strain of my research interest are issues with research practices and research integrity in evidence synthesis.