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Dr Elnaz Yaghini
Division of Surgery and Interventional Science, University College London,
London, UK
  • Senior Research Fellow
  • Department of Surgical Biotechnology
  • Div of Surgery & Interventional Sci
  • Faculty of Medical Sciences
UCL Subsidiary Supervisor

I am a Senior Research Fellow at the Division of Surgery and Interventional Science, University College London (UCL). I did my undergraduate training in 'Clinical Medicine'. Following the completion of my degree in medicine and clinical training, I carried out a PhD in 'Nanomedicine' at UCL. I subsequently started postdoctoral research at UCL in collaboration with Nanoco Technologies Ltd on biomedical applications of novel fluorescent nanoparticles. Afterwards, in collaboration with Bath University I investigated light-triggered drug delivery to cancer cells funded by the BBSRC. My current project supported by Innovate UK is a translational multidisciplinary research programme and involves collaboration with scientists, clinical academic staff and commercial partners. 

Research Summary

As I originally qualified in Clinical Medicine, I have always been particularly interested in translational interdisciplinary research. My career goal is to develop an innovative multimodal optical imaging technique for intraoperative image-guided surgery of tumours. Towards this, my research has focused on the following themes:  

1) Development of novel targeted fluorescent dyes and nanoparticles for intraoperative detection of tumour margins, small metastatic lesions and sentinel lymph nodes. 

2) Investigation of therapeutic applications of a wide range of novel peptide/antibody conjugated nanoparticles and fluorescent dyes in in vitro 2D and 3D constructs and in vivo preclinical tumour models.

3) Preclinical in vivo biodistribution, pharmacokinetic modelling, excretion and toxicology studies of newly developed contrast agents.

4) Preclinical in vivo imaging: using various in vivo imaging modalities to investigate the specificity and sensitivity of the novel theranostic agents for diagnosis and treatment of cancer in preclinical in vivo tumour models.

Teaching Summary

November 2017 - present: Fellow of the Higher Education Academy (FHEA).

I have been awarded (full) Fellow of the Higher Education Academy, which was awarded for my teaching contributions to undergraduate and postgraduate courses, Knowledge Exchange/Transfer activities and supervision of PhD and MSc students. 

I am supervisor for PhD students and I am a member of PhD Thesis Committees. I have a track record of supervising MSc students on various subjects as primary supervisor and I am a personal tutor for postgraduate students. 

I am a tutor for the Nanotechnology and Regenerative Medicine MSc course run by the Division of Surgery and Interventional Science and deliver lecture for the Nanotechnology in Medicine module, which is shared with the Nanomedicine module of the Applied Medical Science BSc and Medical Engineering and Science BSc. I examine the poster and oral presentation coursework for these modules. I act as viva examiner for MSc projects and chair viva exams, and am a member of theMSc/PG Cert Nanotechnology & Regenerative Medicine Board of Examiners. 

Programme Lead: Student Selected Component module for 2nd year MBBS students entitled ‘Nanotechnology and Regenerative Medicine’:

As Programme Lead, my responsibilities have included designing and management of the programme, liaison with UCL MBBS Office, arranging the lectures schedules and delivering lectures. My other major tasks as the Programme Lead have been designing the coursework and its assessment. Throughout the course, I have worked closely together with students and student representatives to complete key tasks towards curriculum reform. In addition, I have efficiently managed the coursework assessment process. 

  Research Associate Division of Surgery and Interventional Science, University College London (UCL), United Kingdom
OCT-2017 Senior Research Fellow Division of Surgery and Interventional Science, University College London (UCL), United Kingdom
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