I have obtained my PhD degree in Biology with a specialisation in Neurobiology from McGill University (Montreal, Canada) in the laboratory of Dr. Salvatore Carbonetto. My thesis work was selected for the Dean's honour list and I was awarded the Gordon A. Maclachlan prize for contributions to the field of biological and health sciences. My thesis focused on the role of dystrophin and associated proteins in muscle development and synapse formation. 

I then joined the laboratory of Prof. Louis Kunkel at the Boston Children's Hospital and Harvard Medical School (Boston, USA) as an HHMI post-doctoral fellow. My post-doctoral work looked at cells involved in adult muscle regeneration and how they could be harnessed for cell based therapies.

In 2005, I started my own laboratory as an assistant professor at the Research Institute at Nationwide Children's Hospital / The Ohio State University (Columbus, USA). My group was part of the Centre for Gene Therapy where we developed a proteomics-based approach to characterise protein complexes assembled by dystrophin in skeletal and cardiac muscles. This analysis revealed proteins that interact with dystrophin only in the heart. 

In 2016, I was awarded a Marie-Curie senior researcher re-integration fellowship from the EU Horizon 2020 programme and joined the Dubowitz Neuromuscular Centre as a senior lecturer at the Great Ormond Street Institute of Child Health / University College London (London, UK). My current research involves the characterisation of cardiac protein complexes assembled by micro-dystrophin constructs currently being evaluated in four gene therapy clinical trials. We are also investigating signalling pathways and cellular processes associated with heart failure that are perturbed in the absence of dystrophin and are not corrected by current micro-dystrophin gene therapy strategies.