Stelios's research is informed by his multi-disciplinary background in architecture engineering, architectural history and theory, and history and philosophy of science and technology. Focusing on regional architectural practices in relation to globalisation, climate change and resilience, his research also addresses issues of equity, diversity and inclusivity. His monograph Resisting Postmodern Architecture develops novel lines of enquiry to integrate underrepresented architects and sources in 5 other languages into anglophone scholarship. Stelios's historical work reappraises the overlooked ‘periphery’ as an active generator of theory and practice. It has been externally funded by the: European Social Fund, Hellenic Ministry of Culture, Hellenic Ministry of Environment, RIBA, British Council, Greek State Scholarships, Onassis, and Michelis Foundations.

2 of Stelios's sole-authored journal articles are among the all-time top-5 and top-7 articles published in Architectural Histories and Journal of Architectural Education, respectively; another was a finalist runner-up for the biannual EAHN Publication Award in 2018, selected by a jury of world-leading architectural historians. Owing to the national and international engagement of his research, Stelios was selected to represent Greece in DoCoMoMo International in 2018. Earlier, in 2010, he was awarded by the Presidency of the Hellenic Republic as 1 of 12 ‘Exceptional Young Scholars’, selected from leading figures among a national cross-disciplinary pool of candidates. In 2010-12, Stelios was co-investigator within a large collective multi-disciplinary group of researchers on ‘Mutating Characters and Policies of the City Centres of Athens and Piraeus’. Research findings informed public policy, notably the Hellenic Ministry of Environment’s strategic plan for Athens 2030. They also formed the basis of the Onassis Foundation’s European architectural competition ‘Rethink Athens’, for which Stelios was invited to serve as consultant.

Stelios has presented his work in numerous peer-reviewed conferences organised by the Society of Architectural Historians (SAH and SAHGB), European Architectural History Network (EAHN), and International Federation of Philosophical Societies (FISP), among others. He is also regularly invited to: present his research at local and international academic institutions, and other public events; serve as peer reviewer for journals, such as The Journal of Architecture, Footprint and Architectural Research Quarterly, and books, such as The Routledge Handbook of Architecture, Urban Space and Politics; serve as member of the scientific committee of conferences such as ‘Architecture and Endurance’ (Middle East Technical University, EAHN Ankara); write review articles for books in his field of expertise; and mentor early-career researchers through initiatives such as the Research Skills Intercollegiate Network of PhD students in UK institutions (2019).

His research focuses on: postmodern and early digital architectural cultures and imaginaries; cross-cultural modes of regional architectural production; global and planetary architectural historiographies; oral histories of architectural education; resilience in architectural history; architectural discourse production through photography, exhibitions and publications; philosophy, science, technology, storytelling and narrative (from comics and literature to videogames) in architectural histories, theories and practices; and histories of disability and neurodiversity in architecture.