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Dr Gavin Jell
UCL Medical School, Royal Free Campus
9th Floor, Royal Free Hospital,Pond Street
London
NW3 2QG
Appointment
  • Senior Lecturer
  • Department of Nanotechnology
  • Div of Surgery & Interventional Sci
  • Faculty of Medical Sciences
Biography

An interdisciplinary scientist who completed a BSc in Biology, followed by and MSc in Parasitology before becoming interested in the material – biological interactions and completing a PhD (at UCL as part of the Queen Mary IRC in Biomedical Materials) looking at the causes of aseptic loosening of  orthopaedic implants. Using this knowledge on cell-material interactions Gavin was recruited by Prof. Larry Hench’s group at Imperial College London (Department of Materials) as a research associate investigating the use of bioactive glass for regenerative medicine. It was during this time that Gavin also developed an interest in multidisciplinary characterisation of material-cell constructs and together the Prof. Ioan Nottigher investigated the use of Raman spectroscopy for the characterising these interactions.

Gavin Joined Prof. Molly Stevens group in 2005 to continue research on tissue engineering and Raman Spectroscopy (as well as overseeing the creation of the tissue engineering laboratories). After 4 great years publishing on a variety of topics (Bio-Raman in tissue engineering, stem cell, tissue engineering, CNT-polyurethane scaffolds and bioactive glasses) and creating/patenting a new range of HIF-1alpha stabilising bioactive glasses (cobalt and copper releasing glasses). Gavin retuned to UCL to lead a new MSc in Nanotechnology and Regenerative Medicine and develop his own research group.     


Research Summary

My research group (6 PhD, 2 MD, 5 MSc students) is focused on understanding how materials interact within biological environments, in order to create "better" biomaterials; materials that have reduced failure rates and have increased functionality (e.g. promote regeneration). Current areas of research include:

1. Nanomedicine. Understanding how nanoparticle physicochemical properties change biological interactions in different biological environments. 

2. Bone and cartilage tissue engineering. Over 20 high impact publication including Nature Materials.

3. Bioactive glass: Understanding how ions released from bioactive glasses affect bone formation and remodelling, to creating new bioactive glasses with therapeutic ion release

4. Materials for Diabetic and Chronic wound healing.

5. The role of hypoxia and HIF in tissue regeneration and cell survival. 

6. Understanding why biomaterials fail

I’ve published ~50 papers on these topics in leading international journals (e.g. Nature Materials) with an average citation/article of 28.  My success has been recognised globally with international research collaborations (I was appointed Associate Prof. Biomaterials at Nagoya Institute of Technology (NIT) in 2015) and invited talks/keynote at international conferences. My views on medical research have been solicited and reported in national newspapers/broadcasters (e.g. Daily MailCrowd science).

Teaching Summary

  • Programme lead for the MSc in Nanotechnology & Regenerative Medicine (~200 graduates). 
  • Course founder and Director for the BSc/MSci in Medical Innovation & Enterprise
  • Course Director for the iBSc in Surgical Science
  • Education Lead (Division of Surgery)
  • Module Lead; 1) Applied Tissue engineering (PG), 2) Tissue Engineering & Regenerative Medicine, 3) MSc Research Projects, 4) Materials in Medicine, 5) Medical Innovation & enterprise.
  •  Lecture topics include; Nanotechnology, nanotoxicity, stem cells, bioceramics, bone tissue engineering, tissue scaffold design, tissue engineering, biomaterial failure, cell culture, cell-material interactions, angiogenesis, hypoxia, medical innovations, critical analysis of research and growing whole organs.
  • Module Development: Created modules in Applied Biomaterials, Transplantation Science, Tissue Engineering and Regenerative Medicine, Medical Innovation and Enterprise (level I,II & II), Materials in Science
  • Course Development: As Divisional Graduate tutor I oversaw the creation and development of 8 new courses (4 MSc’s, 3 BSc’s, 1 intercalated BSc) and relaunched the iBSc in Surgical Science.  I helped create an innovate cross Medical Faculty MSc/MRes programme (Human Tissue Repair) and enabled the integration of Division of Surgery teaching with Faculty UG courses.
  • Divisional Post Graduate Teaching Assistant (PGTA) Coordinator.  To improve teaching experience and career opportunities I developed and run a course to engage Divisional PhD students, PDRA’s with teaching, together with an online platform to engage PG students with teaching

Appointments
MAY-2013 Lecturer in Nanotechnology & Regenerative Medicine Division of Surgery & Interventional Medicine  , United Kingdom
SEP-2009 – MAY-2013 Teaching Fellow Division of Surgery & Interventional Medicine UCL, United Kingdom
2007 – 2009 Research Associate Materials and Institute of Biomedical Engineering Imperial College London, United Kingdom
2006 – 2007 Lead Research Scientist RepRegen Ltd. ICL Bio-Incubator, United Kingdom
2005 – 2006 Research Associate Materials Imperial College London, United Kingdom
2003 – 2005 Research Associate Centre for Tissue Engineering and Regenerative Medicine Imperial College London, United Kingdom
Academic Background
1998 MSc Master of Science – Parasitology University of Wales, Bangor
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