Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
 More search options
Prof Gary Lye
Bernard Katz 4.06
Department of Biochemical Engineering
Gower Street
Prof Gary Lye profile picture
  • Professor of Biochemical Engineering
  • Dept of Biochemical Engineering
  • Faculty of Engineering Science
Gary is Head of the UCL Department of Biochemical Engineering and Director of the EPSRC Centre for Doctoral Training (CDT) in Bioprocess Engineering Leadership. He is Fellow of the Royal Academy of Engineering (FREng), a Fellow of the Institution of Chemical Engineers (FIChemE), a Senior Fellow of the Higher Education Academy (SFHEA) and recipient of the IChemE Donald Medal.

Other current and previous roles include:
- BioIndustry Association, Science and Innovation Advisory Committee (2019 – to date)
- BBSRC Industrial Biotechnology and Bioenergy Strategic Advisory Panel (2016 – 2020)
- EPSRC Manufacturing the Future Strategic Advisory Team (2017 – 2020)
- EPSRC UK Catalysis Hub Steering Committee (2015 – to date)
- EPSRC CDT in Bioprocess Engineering Leadership (Director, 2009 – to date)
- EPSRC CDT in Sustainable Chemical Technologies Advisory Board, Bath (Chair, 2016 – to date)
- EPSRC CDT in Synthetic Biology Advisory Board, Oxford (2014 – 2019)
- IChemE BioFutures Steering Group and Skills Working Group (2017 - 2018)
- IChemE Biochemical Engineering Special Interest Group Committee (Member, 1999 – 2015, Chair, 2005 - 2009)
- Royal Academy of Engineering Membership Panel (2016 – 2020)
- Royal Academy of Engineering, Teaching of Engineering Ethics Group (2004 – 2006)
- UK Government, Industrial Biotechnology Innovation and Growth Team (2008 – 2009)

Gary joined UCL in 1996 and was a founding member of the UCL Department of Biochemical Engineering in 1998. Prior to UCL he was a Lecturer in Chemical Engineering, University of Edinburgh (1995 - 1996) and a Research Fellow in Chemical Engineering, Imperial College London (1993 - 1995).

Research Summary
Gary’s main contributions are to the Industrial Biotechnology research group and focus on the synthesis of value-added chemicals and pharmaceuticals from renewable feedstocks such as Distillers grains, sugar beet and sugar cane. He is currently leading development of the UCL East Manufacturing Futures Lab with Professor Asterios Gavriilidis (UCL Chemical Engineering), Professor Manish Tiwari (UCL Mechanical Engineering) and Professor Helen Hailes (UCL Chemistry).

Research on biocatalysis and the modelling of single-step and multi-step bioconversion processes has benefitted from long-term collaborations with Professors John Ward, Paul Dalby and Helen Hailes (UCL Chemistry). These collaborative efforts have been recognised by the IChemE Innovation and Excellence Award in Bioprocessing (2010) and the Royal Society of Chemistry Rita and John Cornforth Award in Chemical Biology (2010). Gary has a long-standing interest in automated and microscale bioprocessing techniques (with Dr Frank Baganz and Professor Nicolas Szita) and single-use bioprocess technologies (with Dr Martina Micheletti) to facilitate the rapid design, optimisation and scale-up of biocatalytic processes. These technologies have also been applied in the areas of mammalian cell culture (with Dr Alex Kiparissides), algal bioprocessing (with Dr Brenda Parker) and stem cell expansion and differentiation (with Dr Farlan Veraitch).

Current grants include the EPSRC Centre for Doctoral Training in Bioprocess Engineering (EP/L01520X/1 and EP/S021868/1), the EPSRC Future Biomanufacturing Research Hub (EP/S01778X/1) led by the University of Manchester, a BBSRC grant on Continuous Bio-Production of Commodity Chemicals (BB/N023587/1) with the universities of Nottingham and Cambridge, and a BBSRC-FAPESP grant on Lignin Valorisation in Cellulosic Ethanol Plants (BB/P01738X/1) with the universities of Warwick and Manchester and the National Bioethanol Laboratory (Brazil). He is also a member of the Horizon 2020 MSCA-RISE network on Integrated Process and Product Design for Sustainable Biorefineries with twelve partner institutions across the EU, Brazil, Mexico and the United States.

Gary has had a long-standing involvement with Engineering Conferences International (ECI) having chaired sessions and presented at their Biochemical and Molecular Engineering, Cell Culture Engineering and Single-Use Technologies conferences. He was Co-Chair of the first Single-Use Technologies conference in 2015 with Ekta Mahajan (Genentech).

He is an Editorial Board member of the following journals: Biochemical Engineering Journal (founding member), Biotechnology Letters, Biocatalysis and Biotransformation, Bioprocess and Biosystems Engineering, Journal of Chemical Technology and Biotechnology.

As Director of the CDT in Bioprocess Engineering he has actively supported the development of a number of successful UCL spin-out companies, e.g. Synthace, Puridify, Axitan, and has led on licensing of the department’s Ultra Scale-Down (USD) technologies to Gower labs (with Dr Andrea Rayat).

Teaching Summary

Gary's teaching activities span all years of the various undergraduate and postgraduate degree programmes operated by the department. At undergraduate level he contributes to modules on Design and Professional Skills (Year 1), Fermentation and Bioreactor Engineering (Year 2) and Sustainable Industrial Bioprocessing and Biorefineries (Year 4).

At Masters level he oversees the academic content of the department’s MBI Training Programme for industry (with Dr Naveraj Gill) and contributes to modules on Principles of Fermentation Processes, Rapid Fermentation Process Design and Mammalian Cell Processes. He leads the Advanced Bioreactor Engineering module within the full-time MSc Biochemical Engineering programme.

At doctoral level he is Programme Director for the EngD in Bioprocess Engineering Leadership where he leads the module on Professional and Transferable Skills and contributes to the module on statistical Design of Experiments. The EngD Centre won the IChemE Global Award for Training and Development in 2019.

Gary has held a number of External Examiner roles as follows:
- EngD Biopharmaceutical Bioprocessing, Newcastle University (2012 – 2017)
- MSc Industrial Biotechnology, University of Strathclyde (2014 – 2018)
- MSc Biotechnology, University of Manchester (2011 – 2015)
- MSc Food Biotechnology, University of Reading (2003-2007)

He was previously awarded a Royal Academy of Engineering and ExxonMobil Engineering Teaching Fellowship (1998 – 2001).

Academic Background
2017   ATQ04 - Recognised by the HEA as a Senior Fellow  
1992   Doctor of Philosophy University of Reading
1989   Bachelor of Science (Honours) University of Reading
Please report any queries concerning the data shown on this page to https://www.ucl.ac.uk/hr/helpdesk/helpdesk_web_form.php
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by