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Prof Kurinchi Gurusamy
9th Floor, Royal Free Hospital
Rowland Hill Street
London
NW3 2PF
Appointment
- Professor of Evidence-based Medicine and Surgery
- Department of Surgical Biotechnology
- Div of Surgery & Interventional Sci
- Faculty of Medical Sciences
Role
UCL Principal Supervisor,UCL Subsidiary Supervisor
Biography
I am a Professor of Evidence-based Medicine and Surgery, Head of Research at Division of Surgery and Interventional Science, and Director of Surgery and Interventional Trials Unit at University College London (UCL). A surgeon by background, I currently focus on research and teaching with an aim to achieve high quality healthcare for all.
Research Groups
Research Themes
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Research Summary
Impact of research till date
I am one of the top 2% of the scientists who have published
their research in Medicine since 1960, based on the standardized information on
citations, h-index, co authorship-adjusted hm-index, citations to papers in
different authorship positions and a composite indicator (https://doi.org/10.1371/journal.pbio.3000918).
Systematic reviews
High quality research is necessary to identify the diagnostic tests that are accurate and treatments that are effective. Systematic review of randomised controlled trials in literature is currently considered the best level of evidence in assessing whether a treatment is effective. Among systematic reviews, Cochrane systematic reviews are considered the best quality systematic reviews. I am the first author or contact author in more than 100 Cochrane systematic reviews and an author in more than 150 Cochrane systematic reviews. Overall, at least 50 of my systematic reviews and cost-effectiveness analyses have been used in national or international guidelines indicating that his research is not only of high quality, but also that the research topics I choose are important for patient management.
Randomised controlled trials
In addition to guiding clinical practice, systematic reviews highlight the
evidence gap. I have tried to address these by being involved in the design of
randomised controlled trials and translational research.
Clinical practice guideline development
I have also contributed to the development of several national
or international clinical practice guidelines.
Identifying research priorities that are important to patients and clinicians
Recently, I have been using a more formal approach to
identify the research priorities. I have already completed one on non-alcohol
related liver and gallbladder disorders in UK in partnership with patient
groups in UK. This priority setting partnership has identified research gaps in
this field and allows research to be conducted on topics that are important to
clinicians and patients. This will lead to systematic reviews, randomised
controlled trials, and innovative translational research, and address the
issues that are most important to patients and clinicians. I am also the lead
methodologist for another priority setting partnership in healthcare associated
infections.
Reliability assessment of preclinical research
Only a small proportion of preclinical research translate into clinical benefit. There are significant differences in the effect of interventions observed in animal experiments and that observed in clinical trials; some of the interventions shown to be beneficial in animals have turned out to be harmful in humans. I have developed a tool to assess the reliability of preclinical research study and whether the results of the preclinical study are likely to translate into human benefit. This will be published shortly.
Teaching Summary
Courses
I lead a CPD course in systematic reviews (http://www.ucl.ac.uk/lifelearning/courses/systematic-reviews-health-disease-online)
and developed the Research Methodologies and Transferable Skills course in its
current format (https://www.ucl.ac.uk/module-catalogue/modules/research-methodologies-and-transferable-skills-SURG0002).
Academic Background
| ATQ03 - Recognised by the HEA as a Fellow | |||
| PGCE. |
