Email: portico-services@ucl.ac.uk
Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
- Professor of Statistical Methods for Medicine
- Inst of Clinical Trials &Methodology
- Faculty of Pop Health Sciences
I moved at the start of 2017 to a new position as Professor of Statistical Methods for Medicine at the Medical Research Council Clinical Trials Unit at University College London, UK. This follows 16 years as a programme leader at the Medical Research Council Biostatistics Unit in Cambridge. I originally studied mathematics at Cambridge University, and my first career was as a teacher of mathematics in The Gambia, Cambridge and London. I obtained my MSc in statistics from University College London, where I subsequently worked in the Department of Epidemiology and Public Health. I was then Senior Lecturer in the Medical Statistics Unit at the London School of Hygiene and Tropical Medicine. I received my PhD by publications in 2011.
I am a medical statistician with an interest in developing new methodology for design and analysis of clinical trials, meta-analysis and observational studies.
I chair the Unit’s Methodology theme, which comprises four programmes of trial-related research: Design, Conduct, Analysis and Meta-analysis. I lead the Design programme and co-lead the Analysis and Meta-analysis programmes.
I am particularly interested in methods for design of non-inferiority and other trials, including the non-inferiority frontier for non-inferiority trials with uncertain control event rate; the personalised randomised controlled trial (PRACTical) for settings without an accepted standard of care; and the combination of factorial and multi-arm multi-stage trials. Other interests in trials are in causal inference, for example to correct for departures from randomised treatment.
I have worked for many years in missing data, where I have contributed to the widespread use of multiple imputation and am now developing extensions for missing-not-at-random data. I am also particularly interested in meta-analysis and network meta-analysis, where I have developed methods for assessing and testing inconsistency. I co-wrote a tutorial on simulation studies. I have written a range of Stata software.
I teach various short courses including Practical use of multiple imputation to handle missing data in Stata and Using simulation studies to evaluate statistical methods.
01-JAN-2017 | Professor of Statistical Methods for Medicine | MRC Clinical Trials Unit at UCL | UCL, United Kingdom |