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Mr Julien Baruteau
Great Ormond Street Institute of Child Health
30 Guilford Street
Tel: 020 7242 9789
  • Senior Clinical Research Associate
  • ICH Genetics & Genomic Medicine Prog
  • UCL GOS Institute of Child Health
  • Faculty of Pop Health Sciences

Dr Baruteau is a clinician scientist working in the group of Paul Gissen at the Great Ormond Street Institute of Child Health and a Clinical Fellow in Metabolic Medicine at Great Ormond Street Hospital for Children in London. He graduated as a paediatrician in 2008 and gained experience in Inherited Metabolic Diseases in Paris and Toulouse before joining the Metabolic team at Great Ormond Street Hospital for Children as a clinical fellow in 2012. He gained experience in Liver Cell Therapy in Metabolic Diseases in Pr Sokal's laboratory, Catholic University of Louvain, Brussels, in Belgium in 2011. In 2013, he was awarded a Research Training Fellowship by Action Medical Research Charity, which showed a successful proof of concept of AAV gene therapy in a mouse model of argininosuccinic aciduria, a liver inherited metabolic diseases belonging to the urea cycle disorders. Julien was awarded his PhD in 2017 for this work supervised by Dr Simon Waddington, Dr Philippa Mills and Prof Paul Gissen. Since 2015, he is collaborating with Prof Alexander at the Children Medical Research Institute in Sydney and Prof Paul Gissen to set up a clinical trial for paediatric patients affected by the most common urea cycle defect, ornithine transcarbamylase deficiency.

Research Themes
Research Summary

Dr Baruteau has an interest in clinical translation of novel therapies for inherited metabolic diseases in paediatrics. He is currently developing translational programmes of gene therapies for paediatric patients with liver inherited metabolic conditions, especially urea cycle defects.

Teaching Summary

Teaching activities:

- Supervision of MSc students and medical students for elective lab training

- Supervision of Junior doctors in training

Academic Background
2012 DM Doctor of Medicine – Cell Biology Universite Paul Sabatier (Toulouse III)
2008 DM Doctor of Medicine – Paediatrics Universite Paul Sabatier (Toulouse III)
2004 BMBS Bachelor of Medicine & Bachelor of Surgery – Medicine Universite de Bourgogne
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