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Prof Jonathan Ashmore
Department of Neuroscience, Physiology and Pharmacology
University College London
London
WC1E 6BT
Tel: 020 7679 2141
Fax: 020 7813 0530
Prof Jonathan Ashmore profile picture
Appointment
  • Bernard Katz Professor of Biophysics
  • Neuro, Physiology & Pharmacology
  • Div of Biosciences
  • Faculty of Life Sciences
Biography

Originally trained as theoretical physicist (PhD supervisor Tom Kibble), I became a laboratory scientist after a short postdoctoral fellowship with Abdus Salam at ICTP Trieste. I have worked on synaptic mechanisms in the retina in the Dept of Biophysics, UCL and at UCSF, but I have been researching hearing mechanisms since 1980, first at the University of Sussex and then at  Bristol University, where I was promeoted to professor  in 1993. I moved to UCL in 1996.
I  was a founder member of CoMPLEX  (UCL's Centre for Mathematics and Physics in the Life and Experimental Sciences). I was also a founder member of the UCL Ear Institute (in 2001).
I have been President of the Physiological Society (2012-2014) and I am currently Director of the London Interdiscplinary Doctoral Programme (LIDo-DTP).

Research Summary

My work addresses a variety of cellular mechanisms of hearing. Using a variety of biophysical techniques I work on the mechanisms of electromotility in cochlear outer hair cells. Using confocal imaging I have been working on the mechanisms of synaptic release at the ribbon synapse of the inner hair cells, combining electrophysiology and multiphoton imaging. Using large scale computational models I work on the patterning of electrical current flow in the cochlea during stimulation by sound.  I have an  interest in potassium channel function in early auditory processing and the nature and origin of tinnitus and have published in the area. 
A further recent research activity is an investigation of the signalling mechanisms in cancer with a collaboration with groups outside UCL. The research links in to  a long standing interest in calcium mechanisms and  cellular imaging

Teaching Summary

I have lectured at undergraduate and graduate levels most of my academic career on wide range of physiological topics, not just on sensory neuroscience. 
I am currently co-organiser of a 3rd year module, the Cellular Basis of Brain Function, but also lecture on MSc Neuroscience, on the Principles of Biology and to Audiology Students.
I have lectured internationally, in France, in Italy and most recently in India (2019) and in Iran (2019). I have been a Faculty member of the biannual Woods Hole MBL course, The Biology of the Inner Ear (2007-present).


Appointments
01-AUG-1996 Bernard Katz Professor of Biophysics Neuroscience, Physiology and Pharmacology UCL, United Kingdom
Academic Background
1974   Master of Science University College London
1971   Doctor of Philosophy Imperial College of Science, Technology and Medicine
1969   Diploma of the Imperial College Imperial College of Science, Technology and Medicine
1968   Bachelor of Science University of Sussex
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