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Prof Jasminka Godovac-Zimmermann
677/1
Proteomics&Molecular Cell Dynamics,University College London Center for Nephrology
Royal Free Campus, Rowland Hill St
London
NW3 2PF
Tel: +44 207 472 6200
Appointment
- Emeritus Professor of Protein Biochemistry
- Div of Medicine
- Faculty of Medical Sciences
Biography
Jasminka Godovac Zimmermann is Professor in the Faculty of Medicine at University College
London, UK and Head of the Molecular Dynamics Group. She is a protein chemist
trained at the Max-Planck Institute for Biochemistry in Germany. She worked in
Australia, Germany and the UK. She works on Proteomics in Systems Biology, Medical
Therapeutics and Medical Aetiology with a focus on cancer proteomics and the complexity of
eukaryotic proteomes. She is an author of over 120 research papers and reviews
and over 100 presentations. She is also a co-founder of two biotechnology companies.
trained at the Max-Planck Institute for Biochemistry in Germany. She worked in
Australia, Germany and the UK. She works on Proteomics in Systems Biology, Medical
Therapeutics and Medical Aetiology with a focus on cancer proteomics and the complexity of
eukaryotic proteomes. She is an author of over 120 research papers and reviews
and over 100 presentations. She is also a co-founder of two biotechnology companies.
Research Groups
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Research Summary
Proteomics in Systems
Biology, Medical Therapeutics and Medical Aetiology
Cellular systems
offer an unparalleled ability to control, manipulate and experiment with
complex living systems. We address the influence of diversity (protein form
and/or function), quantity (abundance), space (subcellular spatial
distribution) and time (dynamic responses) at the cellular level using high
throughput, quantitative mass spectrometry based proteomics. Our current
applications include several areas of investigation in cancer and the genetic
theory of viral infection:
A) Complex, dynamic spatial organization of
subcellular biology in relationship to the energetic/integrative functions of
mitochondria, nuclear-mitochondrial coordination and the nature of their role
in cancer and other diseases.
B) The complexity of form and subcellular distribution
of proteins and pathways that relate the cell cycle and metabolic status of
cancer cells.
C) Proteomics methods for detection/analysis of functional networks across human populations with genetic variability in determining susceptibility to, consequences of and potential diagnostic/therapeutic approaches in viral infections.
Teaching Summary
Supervising and teaching post-graduate students in proteomics, mass spectrometry, cancer, cell cycle, molecular biology and protein chemistry.
