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Dr James Irving
Dr James Irving profile picture
Appointment
  • Senior Research Associate
  • Respiratory Medicine
  • Div of Medicine
  • Faculty of Medical Sciences
Biography
I have technical expertise in areas which include: structural biology including protein crystallography, biochemistry including polymerization and aggregation kinetics, biophysics including fluorescence spectroscopy and electron paramagnetic resonance spectroscopy, computational methods including single-particle reconstruction from electron microscopy data, molecular modelling and image processing, and methods to assess protein-protein and protein-ligand interactions. I have supervised several Masters’ and PhD students to degree completion as well as postdoctoral scientists. I have been actively involved in collaborations with pharmaceutical companies with the purpose of developing a drug to prevent polymerization of alpha-1-antitrypsin in the liver of people with alpha-1-antitrypsin deficiency.
Research Summary

I utilise a combination of structural biology, biochemistry, biophysics and computational biology to understand protein biological function and dysfunction. 

ORCID iD iconhttps://orcid.org/0000-0003-3204-6356

Teaching Summary
Guest lecturer, MSc (Drug Design)

Guest lecturer, MSc (Respiratory Clinical Science)

Appointments
10-NOV-2020 Honorary Research Fellow Department of Biological Sciences Birkbeck College, United Kingdom
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