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Prof James Moon
Barts Heart Centre
West Smithfield
London
EC1A 7BE
Tel: 07813217844
Appointment
  • Professor of Cardiology
  • Clinical Science
  • Institute of Cardiovascular Science
  • Faculty of Pop Health Sciences
Biography

James is a Professor of Cardiology UCL, London and the Clinical Director of Imaging at the newly opened Barts Heart Centre (BHC). Formerly, he set up and lead the Heart Hospital Imaging Centre, a dedicated cardiac MRI department performing 3500 scans a year with a triple focus on clinical scanning, research and education.

The new Barts Heart Centre has 3 dedicated CMR scanners (2 1.5T Aeras and a 3T Prisma). The centre is at scale – estimates of annual activity are 9,000 CMR scans, 3000 nuclear scans, 3000 CT scans and 40,000 echos.

Trained at Cambridge and Oxford, his MD at Imperial was ‘myocardial tissue characterization by CMR’. His current research group of 10 fellows  have particular interests in measuring diffuse myocardial fibrosis (health, disease); iron, fat infiltration and amyloid using "T1 mapping". He has published more than 200 papers and works in partnership with Pharma to develop surrogate endpoints for clincical trials including first in man studies. Another interest is in making scans faster/cheaper and in improving/maintaining quality as CMR expands. He set up and leads the international T1 mapping development group aiming to "coordinate activity to the goal of being able to change therapy using CMR endpoints".  He is a former board member of SCMR, the current president elect of the British equivalent, BSCMR. He is a former member of NICE.

Education interests are key to the group and significant successes include the setting up of web resources (SCMR video-on-demand, case of the week, online Moodle training - http://education.scmr.org/), as well as local hands-on training courses for upto 4 fellows at any one time - please see here.

http://www.scmr.org/Education/fellowtraining.html#.VcM9erlRGT0.


Research Summary

Research interests:
I am interested in better understanding heart disease to improve patient care through therapies with a particular interest in myocardium. I am particularly know for the use of cardiac MRI and in developing mapping techniques to bridge clincial and basic investigators. My team focus on technical development, translation, creation and standardization of new biomarkers, delivery of surrogate endpoints, defining new diseases, quality control, training, enabling others.

Senior academic Partners:
1.       Dr Peter Kellman, NIH (appointed visiting professor UCL and Barts)
2.       Dr Charlotte Manisty June 2014: Senior Lecturer in Heart failure and CMR
3.       Dr Marianna Fontana, Director Royal Free Hospital CMR
4.       Dr Guy Lloyd December 2014: Echo lead (former president BSE
5.       Dr Christos Bourantas (invasive imaging)
6.       Leon Menezes, lead in nuclear cardiology across UCLH/Barts
7.       Dr Gaby Captur, BRC post doc lecturer in rare diseases
8.       Dr Tom Treibel, UCL lecturer
In collaboration with Dr Francesca Pugliese (CT) and Prof Steffen Petersen


Current Imaging Facilities:
Barts Heart Centre, the largest cardiac centre in Europe. Opened in May 2015, serving a population of upto 6million.  There are 250 beds, 9 operating theatres and 9 cath labs.
Capacity: Barts Heart Centre: CMR: 2x Aera, 1x Prisma; CT: 1x Force; Echo: 15 machines; Nuclear: 4 sites inc PET-CT. Capacity (pa): 8000 CMRs, 4500 CTs, 40,000 echos, 2500 nuclear cardiac scans.
Chenies Mews Imaging Centre, part of the UCL phenotyping centre: 2x CMR (1xAera, 1xPrisma): 8 clinic rooms, DEXA, Echo, CPEX, and space for 30 researchers (Professors Alun Hughes and Nish Chaturvedi teams).

Example current projects are:
AS700 (7 centres)
Fabry400 (4 centres)
T1MES program (79 centres)
REDCap for UK research (250 projects),
CMR insights in athletes
Cardio-orthopaedics
MRI for pacemakers
Perfusion mapping collaboration (5 sites)
Developing world CMR (5 countries)
NIH collaboration for clinical validation of new sequences

James has 250 papers on Pubmed, (41 in 2017). Google citations 15,643; h-index 56.


Teaching Summary

I was for 5 years web editor of www.scmr.org - the leading web based source of information on cardiac MRI. I founded and am a director of a heart hospital based course: preparation and revision for the british society of echocardiography exam I set up the visiting 3 month fellows program at the heart hospital imaging centre where national and international students learn CMR I have set up a moodle based cmr academy at http://education.scmr.org/

Academic Background
2003 MD Doctor of Medicine – Magnetic Resonance Imaging University of London
1998 MRCP Member of the Royal College of Physicians – Medicine Royal College of Physicians
1995 MB BCh Bachelor of Medicine, Bachelor of Surgery – Medicine University of Oxford
1992 BA Bachelor of Arts – Medicine University of Cambridge
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