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Prof James Moon
Barts Heart Centre
West Smithfield
Tel: 07801283812
Prof James Moon profile picture
  • Professor of Cardiology
  • Clinical Science
  • Institute of Cardiovascular Science
  • Faculty of Pop Health Sciences

James is CMR lead at Barts Heart Centre,  Medical director of Chenies Mews Imaging Centre and CEO of Mycardium AI Ltd, a UCL spinout delivering cardiovascular corelab AI analytics. Formerly, he set up and lead the Heart Hospital Imaging Centre. The centre and its affiliated CMR services are the largest in the world (28,000 scans a year). 

Trained at Cambridge and Oxford, his MD at Imperial was ‘myocardial tissue characterization by CMR’. His research group have particular interests in heart muscle and conditions that affect it such as cardiomyopathy, Fabry, amyloid, valve disease, cardio-oncology, athleticism and aging which he measures using developed techniques (LGE, T1 mapping, perfusion mapping). A major current work program is measuring the heart using developed AI that exceeds human performance. He has published more than 500 papers and works inpartnership with Pharma to develop surrogate endpoints for clincical trials including first in man studies. Another interest is in making scans faster/cheaper and inimproving/maintaining quality. He set up and led the international T1 mapping development group, mrimypacemaker and CMR for lower middle income countries.

He is a former member of NICE, former President of BSCMR and a former and current board member of SCMR

Research Themes
Research Summary

Research interests:
I am interested in better understanding heart muscle diseases and linking this to therapy. I am particularly know for cardiac MRI. The 500+ papers my team and I have published focus on technical development, AI, translation, creation and standardization of new biomarkers, delivery of surrogate endpoints, defining new diseases, quality control, training, enabling others.

In 2022, I founded Mycardium AI ltd to accelerate AI delivery with a particular focus on corelab AI imaging measurement to accelerate drug development.

Senior academic team/collaborators:
1. Professor Peter Kellman, NIH (visiting professor UCL and Barts)
2. Professor Marianna Fontana, Deputy director, National Amyloid Centre and Director, CMR
3. Professor Charlotte Manisty: Cardio-oncology lead, UCL and Barts
4. Dr Gaby Captur, senior lecturer in rare diseases and health/aging, UCL, Barts and Royal Free
5. Dr Tom Treibel, senior lecturer, BHF Intermediate, UCL and Barts
6. Dr Rhodri Davies, senior lecturer, machine learning for medical imaging, UCL and Barts
7. Dr Luis Lopes, senior lecturer, genetic cardiomyopathy UCL and Barts
8. Dr Guy Lloyd December: Echo lead (former president BSE, BSE secretary)
9. Dr Christos Bourantas (invasive imaging) UCL and Barts
10. Dr Leon Menezes, lead in nuclear cardiology across UCLH and Barts 
11. Dr Viviana Maestrini, senior lecturer, La Sapienza, Rome
12. Dr Rebecca Kozor, senior lecturer, director of CMR, University of Sydney, Australia
13. Dr Camilla Torlasco, senior lecturer, Università degli Studi di Milano-Bicocca, Director of CMR, Milan

Research metrics:
H index (google scholar) 98, citations 43,000, ~500 papers on Pubmed
Current Imaging Facilities:
Barts Heart Centre, the largest cardiac centre in Europe serving a population ~6million.  250 beds, 9 operating theatres and 9 cath labs.
Capacity: Barts Heart Centre: CMR: 2x Aera, 1x Prisma; CT: 1x Force; Echo: 15 machines; Nuclear: 4 sites inc PET-CT. Capacity (pa): 9000 CMRs, 5500 CTs, 60,000 echos, 2500 nuclear cardiac scans.
Chenies Mews Imaging Centre, part of the UCL phenotyping centre: 2x CMR (1xAera, 1xPrisma): 8 clinic rooms, DEXA, Echo, CPEX, and space for 30 researchers (Professors Alun Hughes and Nish Chaturvedi teams).
Example current projects:
Mycardium Al Ltd: CMR AI based corelab services
COVIDsortium (20 papers inc 1 nature, 3 Science, 3 Lancet, 1 EHJ, 1 Circulation)
Rapid CMR for Lower Middle Income Countries
(9 countries)
MRI for pacemaker patients

Perfusion mapping collaboration (15 sites)
NIH collaboration for clinical validation of new sequences
AS700 (7 centres - including 166 biopsies in aortic stenosis to date)
Fabry400 (4 centres)
T1MES program (79 centres)
REDCap for UK research (250 projects),
CMR insights in athletes

Teaching Summary

I was for 5 years web editor of www.scmr.org - the leading web based source of information on cardiac MRI. My team has recorded 1000s of CMR lectures over the last decade. For 10 years, I have run a visiting course fellowship for CMR.  I lead a program - www.rapidcmr.com to initiate rapid CMR in LMIC countries embedded in healthcare, currently active in 10 countries.  We train people in MRI for pacemakers: www.mrimypacemaker.com

Academic Background
2003   Doctor of Medicine University of London
1998   Member of the Royal College of Physicians Royal College of Physicians
1995   Bachelor of Medicine, Bachelor of Surgery University of Oxford
1992   Bachelor of Arts University of Cambridge
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