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Dr Jan-Willem Taanman
U3/101, U3/102
UCL - Royal Free Campus
Rowland Hill Street
Tel: 020 7794 0500
Fax: 020 7472 6829
  • Reader in Clinical Neurosciences
  • Clinical and Movement Neurosciences
  • UCL Queen Square Institute of Neurology
  • Faculty of Brain Sciences
Research Summary

My research focuses mainly on the biogenesis of mitochondria and the role of mitochondria in disease. Historically, I have worked on: (1) structure-function relationships and assembly of the terminal mitochondrial respiratory chain enzyme complex cytochrome-c oxidase, and (2) mitochondrial DNA depletion syndrome. Since 2005, I have also studied mitochondrial aspects in Parkinson’s disease. More recent research projects include: (1) the biogenesis of mitochondrial respiratory chain complex I, (2) the glycolytic switch in the progression of colorectal cancer, (3) the influence of mitochondrial DNA level on cellular energy metabolism, (4) the generation of stem cell models of Parkinson's disease, and (5) the mitochondrial metabolic signature in peripheral tissues of Huntington’s disease patients.

Teaching Summary

Supervision of research projects of BSc students (Biochemistry, Biomedical Sciences, Biological Sciences, Biotechnology, Genetics, Human Genetics, Molecular Biology, Physiology) and MSc students (Clinical Neurosciences).

01-OCT-2008 Reader in Clinical Neurosciences Clinical Neurosciences UCL Institute of Neurology, United Kingdom
01-OCT-2001 – 30-SEP-2008 Lecturer Clinical Neurosciences UCL Institute of Neurology, United Kingdom
01-OCT-1996 – 30-JUN-2001 Career Development Research Fellow Clinical Neurosciences UCL Royal Free and University College Medical School, United Kingdom
01-OCT-1994 – 30-SEP-1996 Research Fellow Clincial Neurosciences Royal Free Medical School, United Kingdom
Academic Background
1991 PhD Doctor of Philosophy – Cell Biology and Biochemistry To be updated
1985 MAS Masters – Plant Pathology To be updated
1982 BSc Bachelor of Science – Plant Pathology To be updated
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