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Dr Kristine Arnvig
Tel: +44 (0) 2076792242
Dr Kristine Arnvig profile picture
  • Associate Professor
  • Structural & Molecular Biology
  • Div of Biosciences
  • Faculty of Life Sciences

I received my scientific training at The University of Copenhagen, Denmark (BSc and Cand Scient~M.Phil) and at the National Institute for Medical Research (NIMR now part of The Crick), UK (PhD), where I worked for several years as a staff scientist before starting my own lab at UCL in 2013. 

Research Summary

Mycobacterium tuberculosis (Mtb) remains one of the biggest killers throughout times and the world’s number one killer due to a single infectious agent. Yet, very little is known about Mtb RNA biology and its role in host-pathogen interactions. Research over the last two decades has demonstrated that RNA is much more than an intermediary between genes and proteins. This multi-functional molecule has turned out to perform regulatory roles that affect all levels of gene expression in all domains of life. Bacterial RNA-based regulators (riboregulators) come in different shapes and sizes including small RNAs (sRNAs), antisense RNA, 5’ leaders and riboswitches, and they form an extensive network of co- and post-transcriptional regulators that modulate and fine-tune the protein-based regulation of gene expression mediated by e.g. transcription factors. Our aim is to obtain a deeper understanding of the basic (RNA) biology of Mtb, which in time will further the understanding of gene expression control and support the development of novel diagnostics, drugs and vaccines. By combining high-throughput methods with a range of genetic and molecular biology approaches, we aim to characterize the expression, processing, degradation and regulatory role of different Mtb riboregulators.

Teaching Summary

I am module organiser for BIOC0004 (Introduction to microbiology), where I also teach and supervise laboratory practicals.  Moreover, I teach on BIOC0003, BIOC0005, BIOC0014 and BIOC0020. I supervise third year student literature projects and fourth year MRes and MSci lab projects.

01-JUL-2019 Associate professor SMB UCL, United Kingdom
01-APR-2013 Lecturer Structural Molecular Biology UCL, United Kingdom
Academic Background
2015   ATQ03 - Recognised by the HEA as a Fellow  
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