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Prof Krista Rombouts
Prof Krista Rombouts profile picture
Appointment
  • Professorial Research Associate
  • Inst for Liver and Digestive Hlth
  • Div of Medicine
  • Faculty of Medical Sciences
Biography

Prof Rombouts was awarded her PhD in Medicine at the Free University of Brussels (VUB), Brussels, Belgium with training scholarships for the Liver Research Center, Albert Einstein College of Medicine, University of Yeshiva, NY, U.S.A. and University of Goettingen, Germany.  Since then, Prof Rombouts was a recipient of the renowned Sheila Sherlock post-doctoral Fellowship of the European Association for the Study of the Liver (EASL) carried out in the laboratories of Hepatology, Internal Medicine at the University of Florence, Italy. In November 2012, Prof Rombouts joined the Institute for Liver and Digestive Health, Regenerative Medicine and Fibrosis Group, and is Head of Centre for Tissue Repair and Regeneration, University College London (UCL), UK.

Research Summary

Professor Rombouts’s current research interests is fibrogenesis with focus on Hepatic Stellate Cell behaviour and liver cancer cell biology with a specific focus on fibrotic stroma  – cancer cell interaction. Further interests include genetic polymorphism heterogeneity – cell behaviour in diseases such as Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis. Her research remit includes both the ECM matrix and cellular components of tissues, with a specific focus on cell behaviour in 2D and 3D cell culture systems for improvement of new target identification and drug development. Recent research projects also include mesenteric fibrosis in small intestinal neuroendocrine tumors: pathogenesis and potential therapeutic targets.

Teaching Summary

Prof Rombouts, Fellow of the Higher Education Academy (HFEA) is module lead for MSc/MRes in Human Tissue Repair at UCL for Tissue Repair and Regeneration and module lead for BSc Applied Medical Sciences for Techniques in Molecular Medicine. Prof Rombouts lectures on various aspects of basic hepatology, research applied hepatology, cell biology, molecular cellular biology, physiology and pathophysiology to students on BSc and MSc degree courses. This involves creating online material, face-to-face lecturing, journal clubs and undertaking various aspects of student assessment and feedback. Prof Rombouts is a formal PhD student supervisor and has supervised numerous PhD, MRes, MSc and BSc students in the laboratory.

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